复方野马追胶囊抗呼吸道合胞病毒研究

目的 观察复方野马追胶囊对呼吸道合胞病毒（RSV）感染及炎性因子IL-8释放的抑制作用。方法 采用细胞病变（CPE）观察和活细胞染色方法，观察复方野马追胶囊对呼吸道合胞病毒感染细胞的保护。同时，通过ELISA法测定培养上清IL-8的变化。结果 复方野马追胶囊对呼吸道合胞病毒感染有抑制作用，其中以治疗法效果最为明显。同时该药对呼吸道合胞病毒感染后引起的IL-8释放也有明显抑制作用。结论 复方野马追胶囊具有明显的体外抗呼吸道合胞病毒感染、降低感染后气道炎症因子释放的作用。

Study on Fufang Yemazhui Capsula against respiratory syncytial virus

Objective To observe the inhibition of Fufang Yemazhui Capsula on respiratory syncytial virus (RSV) infection and the release of inflammatory factors IL-8. Methods Cytopathic effect (CPE) observation and living cells staining were employed to investigate the protection of Fufang Yemazhui Capsula to the infected cells. ELISA was used to detect the concentration of IL-8. Results Fufang Yemazhui Capsula obviously inhibited the RSV infection, especially after viral infection. And it also could significantly inhibit the release of IL-8 in RSV-infected A549 cells. Conclusion Fufang Yemazhui Capsula shows the significant antiviral effect in vitro and takes a role in controlling the release of airway inflammatory factors of RSV infection.