| 海洋天然产物研究与新药开发 |
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| 引用本文： | 史清文,李力更,王于方.海洋天然产物研究与新药开发[J].医学教育探索,2010,33(3):165-174. |
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| 作者姓名： | 史清文 李力更 王于方 |
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| 作者单位： | 河北医科大学 药学院 天然药物化学教研室，河北 石家庄 050017 |
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| 基金项目： | 河北省引进留学人员基金（2008-2010）、河北省自然科学基金（08B032）、河北省卫生厅基金（05089）以及河北省中医药管理局基金（2006053）、河北医科大学教育科学研究重点课题（09zd-17）资助项目。 |
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| 摘 要： | 近年来海洋天然产物越来越引起科学家们的关注。在浩瀚的海洋中存在着大量超乎人们想象的化学结构新颖、生物活性多样、作用机制独特的次生代谢产物。海洋天然产物已成为发现重要先导药物的主要源泉。本文主要探讨近年来发现的重要的海洋天然活性产物以及在新药开发中所起的作用。
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| 关 键 词： | 海洋天然产物 新药 研究与开发 |
Research of marine natural products and new drugs development |
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| SHI Qing-wen,LI Li-geng,WANG Yu-fang.Research of marine natural products and new drugs development[J].Researches in Medical Education,2010,33(3):165-174. |
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| Authors: | SHI Qing-wen LI Li-geng WANG Yu-fang |
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| Institution: | Department of Medicinal Natural Product Chemistry, College of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang 050017, China |
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| Abstract: | Marine natural products have increasingly captured the attention of scientists in recent years. There are great amount of secondary metabolites including unique chemical structure, various potent biological activities, and special physiological mechanism in the vast oceans. Marine natural products have become one of the most important resources of novel leading compounds especially for the critical diseases. This article mainly discussed the roles of important marine natural products and development of new drugs. |
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| Keywords: | marine natural products new drugs research and development |
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