| 高分子药物－可乐定阴离子丙烯酸树脂盐的研制及释药性能探索 |
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| 引用本文： | 朱瑞宜,赵德仁,齐瑜群. 高分子药物－可乐定阴离子丙烯酸树脂盐的研制及释药性能探索[J]. 医学教育探索, 1994, 0(3) |
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| 作者姓名： | 朱瑞宜 赵德仁 齐瑜群 |
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| 作者单位： | 华东理工大学 |
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| 摘 要： | 研制了高分子药物－可乐定阴离子丙烯酸树脂盐并在模拟胃和小肠ｐＨ的缓冲液中进行了高分子药物的溶解释放试验。结果表明其中某些试样能够在微碱性的缓冲液中缓慢溶解释放，可望达到减少用药量。降低副作用和延长药效的目的。
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| 关 键 词： | 高分子药物，可乐定，阴离子丙烯酸树脂，溶解释放 |
Preparation and Propertieds of Clonidine-anionic Resin Polymeric Drug |
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| Zhu Ruiyi,Zhao Deren,Qi Yuqun. Preparation and Propertieds of Clonidine-anionic Resin Polymeric Drug[J]. Researches in Medical Education, 1994, 0(3) |
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| Authors: | Zhu Ruiyi Zhao Deren Qi Yuqun |
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| Abstract: | Five anionic acrylic resins were synthesized by solution Polymerization using methyl methacrylate, methacrylic acid and acrylic acid. The Polymeric drugs of clonidine-anionic acrylic resin have been prepared. The dissolution release test of polymeric drug |
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| Keywords: | Polymeric drug Clonidine Anionic acrylic resin Dissolution release. |
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