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| 丙泊酚对人定量药物脑电图δ频段功率百分比的影响 | |
| 引用本文： | 刘玲玲,王立伟,吴克俭,戴体俊.丙泊酚对人定量药物脑电图δ频段功率百分比的影响[J].徐州医学院学报,2010,30(1):8-10. |
| 作者姓名： | 刘玲玲 王立伟 吴克俭 戴体俊 |
| 作者单位： | 1. 厦门市第二医院麻醉科,福建,厦门,361022 2. 徐州市中心医院麻醉科,江苏,徐州,221009 3. 徐州医学院附属医院脑电图室,江苏,徐州,221002 4. 徐州医学院麻醉学院,江苏,徐州,221002 |
| 基金项目： | 国家自然科学基金，江苏省社会发展科技计划，厦门市卫生局医学科研立项项目 |
| 摘 要： | 目的观察丙泊酚对人定量药物脑电图（QPEEG）δ频段功率百分比的影响。方法青年志愿者20人,每组10人,男女各半,分别静脉注射丙泊酚1.0 mg/kg、1.5 mg/kg,观察比较2组给药前后QPEEG的δ频段功率百分比。结果注射丙泊酚后,2组QPEEGδ频段功率百分比均增加（P〈0.01））,25 min达高峰,约10min恢复。1.5 mg/kg组QPEEGδ频段功率百分比增加幅度大于1.0 mg/kg组（P〈0.05,P〈0.01）。结论丙泊酚可剂量依赖性地增加人QPEEGδ频段功率百分比,提示QPEEGδ频段功率百分比有可能成为监测丙泊酚麻醉深度的指标。 |
| 关 键 词： | 丙泊酚 定量药物脑电图 麻醉深度 监测 δ频段 功率百分比 |
The effects of propofol on the percentage of δ band power of quantitative pharmaco-EEG |
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| LIU Lingling,WANG Liwei,WU Kejian,DAI Tijun.The effects of propofol on the percentage of δ band power of quantitative pharmaco-EEG[J].Acta Academiae Medicinae Xuzhou,2010,30(1):8-10. | |
| Authors: | LIU Lingling WANG Liwei WU Kejian DAI Tijun |
| Institution: | LIU Lingling1,WANG Liwei2,WU Kejian3,DAI Tijun4*(1.Department of Anesthesiology,The Second Hospital of Xiamen,Xiamen,Fujian 361002,China,2.Department of Anesthesiology,Xuzhou Central Hospital,Xuzhou,Jiangsu 2210093.Department of EEG,Affiliated Hospital of Xuzhou Medical College,Jiangsu 221002,4.Department of Anesthetic Pharmacology,Xuzhou Medical College,Jiangsu 221002) |
| Abstract: | Objective To investigate the effects of propofol on the percentage of δ band power of quantitative pharmaco-EEG（QPEEG）.Methods 20 healthy adults were randomly divided into 2 groups（P1.0 ＆ P1.5,n=10 each） and were given iv injections of 1.0 mg·kg-1 or 1.5 mg·kg-1 of prpofol,respectively.The EEG samples were obtained before and at regular intervals following the propofol injections.Power spectral analysis was conducted to check the EEG variations before and after the propofol iv injections.Results The percentage of δ band power of QPEEG significantly increased in both groups（P〈0.01）,reached its peak at 2-5 min,and then returned to normal at 10 min.The increase of the percentage of δ band power of QPEEG in group P1.0 was greater than that in group P1.5（P〈0.05,P〈0.01）.Conclusion Propofol increased the percentage of QPEEG power at δ band in a dose-dependence manner,which suggested that the percentage of QPEEG power at δ band serve as an effective index of anesthesia depth monitering. |
| Keywords: | propofol QEPPG anesthesia depth δ band the percentage of power |
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