| MTT法检测CIK细胞的体外杀瘤活性 |
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| 引用本文： | 李淑艳,杨秀珍,杨凤坤,裴春颖.MTT法检测CIK细胞的体外杀瘤活性[J].齐齐哈尔医学院学报,2003,24(1):3-5. |
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| 作者姓名： | 李淑艳 杨秀珍 杨凤坤 裴春颖 |
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| 作者单位： | 1. 齐齐哈尔医学院生物化学教研室
2. 哈尔滨医科大学免疫教研室,161042 |
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| 摘 要： | 目的：观察CIK（cytokine induced killer)细胞的体外杀瘤活性。方法：以LAK（lympho kine activated killer) 细胞作对比，用MTT法测定并比较CIK细胞与LAK细胞的体外杀瘤活性。结果：CIK细胞的体外杀瘤活性明显优于LAK细胞，杀伤率分别为29％和15％，结论：CIK细胞是一种具有较强杀伤活性的免疫效应细胞，有可能用于抗肿瘤的生物治疗。
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| 关 键 词： | MTT法 检测 CIK细胞 体外杀瘤活性 抗肿瘤作用 肿瘤 生物疗法 |
| 修稿时间： | 2002年2月4日 |
Measure Antitumor Cytotoxicity of Human Cytokine Induced Killer(CIK) Cells in Vitro by MTT Assay |
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| Li Shuyan,et al..Measure Antitumor Cytotoxicity of Human Cytokine Induced Killer(CIK) Cells in Vitro by MTT Assay[J].Journal of Qiqihar Medical College,2003,24(1):3-5. |
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| Authors: | Li Shuyan |
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| Abstract: | Objective To evaluate antitumor cytotoxicity of human cytokine induced killer(CIK) cells in vitro. Methods Compared with LAKcells, measure antitumor cytotoxicity of human cytokine induced killer(CIK) cells and LAK cells in vitro by MTT assay. Results In four hours, CIK cells will possesse a higher antitumor activity in vitro than LAK cells. Conclusions CIK cells are highly efficient cytotoxic effector cells against tumor and may be used for adoptive antitomer immunotherapy. |
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| Keywords: | CIK LAK Antitumor effect |
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