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颈后路单开门椎管扩大成形术临床疗效影响因素的研究
引用本文:黄宇,林晋,黄志鸿,林建华,陈宣维,李丽生.颈后路单开门椎管扩大成形术临床疗效影响因素的研究[J].福建医科大学学报,2016(6):387-391.
作者姓名:黄宇  林晋  黄志鸿  林建华  陈宣维  李丽生
作者单位:1. 福建医科大学附属第一医院骨科,福州,350005;2. 福建卫生职业技术学院医学基础部,福州,350101;3. 福建医科大学基础医学院,福州,350004
基金项目:福建省自然科研基金(13151039),福建省医学创新课题(2014-CX-22),福建省中青年教师教育科研项目(JAT160796),福建省卫计委青年基金(2013-1-31)
摘    要:目的 探讨影响颈后路单开门椎管扩大成形术(ELAP)临床疗效的相关因素. 方法 选取30例采用ELAP治疗并获得24月以上随访的患者,评测患者术前JOA评分、术后末次随访JOA评分,测量患者颈椎管正中矢状径增加距离(SCD)、开门距离(LOS)、开门角度(LOA)、术前颈椎前凸角度(LA),并结合年龄、性别、手术时间、术中出血等参数,研究以上参数之间及其与术后JOA评分改善率的相互影响关系. 结果 患者术前JOA评分平均分为(10.13±2.16),术后JOA评分平均分为(13.97±1.78),JOA评分改善率为(56.22±22.47)%.年龄≥70岁则JOA评分改善率明显下降,与其他年龄组比较,差别有统计学意义(P<0.05);不同性别组之间JOA评分改善率无明显差别(P>0.05);术前、术后JOA评分具有显著正相关(P<0.01);年龄与术前评分间无显著相关,与术后JOA评分具有显著负相关(P<0.05);SCD,LOS及IOA 3者之间呈显著相关(P<0.01);LA与SCD,LOS,LOA无相关;术后JOA评分改善率与LOS呈显著相关(P<0.01),与SCD呈显著相关(P<0.05). 结论 SCD,LOS及LOA 3者之间呈显著相关;术后JOA评分改善率与LOS,SCD呈显著相关;LOS及SCD对ELAP临床疗效有显著影响.

关 键 词:颈椎  椎管    多元分析  回归分析

Analysis of Prognostic Factors Related with the Clinical Outcomes after Expansive Open-door Laminoplasty
HUANG Yu,LIN Jin,HUANG Zhihong,LIN Jianhu,CHEN Xuanwei,LI Lisheng.Analysis of Prognostic Factors Related with the Clinical Outcomes after Expansive Open-door Laminoplasty[J].Journal of Fujian Medical University,2016(6):387-391.
Authors:HUANG Yu  LIN Jin  HUANG Zhihong  LIN Jianhu  CHEN Xuanwei  LI Lisheng
Institution:1.Department of Orthopaedics, The Affiliated First Hospital of Fujian Medical University, Fuzhou 350005, China;
2.Department of Human Anatomy and Histology, Fujian Health College, Fuzhou 350101,China;
3.Department of Basic Medical Science, Fujian Medical University, Fuzhou 350004, China
Abstract:Objective To detect the factors that affect the prognosis of expansive open-door laminoplasty.Methods 30 patients who underwent expansive open-door laminoplasty were selected and were followed upfor more than 24 months.The preoperative JOA scores and the last follow-up JOA scores were obtained.The increase in sagittal canal diameter (SCD),the laminoplasty opening size (LOS),the laminoplasty opening angle (LOA),and C3~C7 lordosis angle (LA)were measured by the imaging data in perioperative period.With consideration of age,sex,operation time and bleeding during the operation,the association among the above mentioned parameters were analyzed.We also analyzed the relationship between those parameters and improvement rate of nerve function postoperatively.Result The preoperative average JOA scores was (10.13±2.16) and the postoperative average JOA scores was (13.97±1.78) at the last follow-up.The average improvement rate of nerve function was (56.22±22.47)%.The analysis showed that when the age was 70 or older,the improvement rate of JOA scores significantly decreased,and the difference in age was statistically significant(P<0.05).There was no significant difference in improvement between different gender groups(P>0.05);The preoperative JOA scores and the postoperative JOA scores were related positively significantly (P<0.01).The age was not related with the preoperative JOA scores,but it was related negatively significantly with the postoperative JOA scores(P<0.05).The SCD,LOS and LOA were related with each other significantly(P<0.01).The LA was not related with the SCD,LOS or LOA;The improvement rate of nerve function and the LOS were related significantly(P<0.01).The improvement rate of nerve function also was related to the SCD(P<0.05).Conclusion The SCD,LOS and LOA are related significantly.The LOSand SCD are related significantly with the improvement rate of nerve function after ELAP.
Keywords:cervical vertebrae  spinal canal  neck  multivariate analysis  regression analysis
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