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Survivin基因蛋白在子宫内膜腺癌组织的表达
引用本文:吴章芳,王云英,吴荔香,许淑霞.Survivin基因蛋白在子宫内膜腺癌组织的表达[J].福建医科大学学报,2003(Z1).
作者姓名:吴章芳  王云英  吴荔香  许淑霞
作者单位:福建省妇幼保健院病理科 福建省妇幼保健院病理科 福州
摘    要:目的 测定 Survivin在子宫内膜腺癌组织中的表达。 方法 采用 SP免疫组织化学方法 ,对 39例子宫内膜腺癌 ,10例子宫内膜增殖症和 10例增殖期子宫内膜进行 Survivin检测。 结果  30例子宫内膜腺癌 Sur-vivin阳性 (76 .92 % ) ,子宫内膜增殖症和增生期宫内膜均阴性。 结论  Survivin可作为子宫内膜腺癌诊断标志物

关 键 词:子宫内膜肿瘤  抑制蛋白

Expression of Survivin in Adenocarcinoma of the Endometrium
WU Zhang\|fang,WANG Yun\|ying,WU Li\|xiang,XU Shu\|xia.Expression of Survivin in Adenocarcinoma of the Endometrium[J].Journal of Fujian Medical University,2003(Z1).
Authors:WU Zhang\|fang  WANG Yun\|ying  WU Li\|xiang  XU Shu\|xia
Institution:WU Zhang\|fang,WANG Yun\|ying,WU Li\|xiang,XU Shu\|xia Department of Pathology,Fujian Provincial Maternity Child Health Institute,Fuzhou\ 350001,China
Abstract:Objective\ To detect the expression of survivin in adenocarcinoma of the endometrium.\ Methods\ The expression of survivin in 39 cases of adenocarcinoma of the endometrium, 10 cases of endometrial hyperplasia and 10 cases of proliferative phase of endometrium were detected by immunohistochemical SP method.\ Results\ There were 76 92% positive rate of survivin in adenocarcinoma of endometrium, otherwrise the endometrial hyperplasia and proliferative phase of endometrium were negative.\ Conclusion\ Survivin gene may be as role of a tumor marker for adenocarcinoma of endometrium.
Keywords:adenocarcinoma of endometrium  survivin
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