福建地区口腔癌预后影响因素的研究

目的探索福建地区口腔癌预后的影响因素。方法采用前瞻性临床随访设计，随访705例口腔癌患者，收集确诊病例的临床资料及随访生存情况，运用COX回归探讨口腔癌预后影响因素的风险比例（HR）及其95%可信区间（CI）。结果性别、文化程度、饮酒、肿瘤家族史、肿瘤大小、肿瘤复发、首诊淋巴结转移、T分期、M分期、组织学分级、手术治疗、口腔卫生是影响口腔癌总体生存期的预后因素（P<0.05）。结论患者的性别、文化程度、饮酒、肿瘤家族史、肿瘤大小、肿瘤复发、首诊淋巴结转移、T分期、M分期、组织学分级、手术治疗、口腔卫生与口腔癌的预后有关。

Study on the Prognostic Predictors of Oral Cancer in Fujian Area

ObjectiveTo explore the factors influencing the prognosis of oral cancer in Fujian area.MethodsAll qualified patients were followed prospectively every 6 months from the time of enrollment of the patients or their family contacts.The clinical and follow-up data of 705 patients were gathered to explore the prognosis factors of oral cancer.Cox regression was used to calculate the hazard ratio and 95% confidence intervals of prognosis factors.ResultsGender, education level, alcohol drinking, family history of cancer, tumor size, tumor recurrence, diagnosis of lymph node metastasis for the first time, T stage, M stage, histological grade, surgical treatment and oral hygiene were prognostic factors affecting the overall survival of oral cancer(P<0.05).ConclusionsThere is association between gender, education level, alcohol drinking, family history of cancer, tumor size, tumor recurrence, diagnosis of lymph node metastasis for the first time, T stage, M stage, histological grade, surgical treatment and oral hygiene and the prognosis of oral cancer.