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黄芪抑制EB病毒壳抗原在体外细胞中表达的作用
引用本文:崔英,邝国乾,岳惠芬,刘名光,梁新强.黄芪抑制EB病毒壳抗原在体外细胞中表达的作用[J].广西医科大学学报,2001,18(6):791-792.
作者姓名:崔英  邝国乾  岳惠芬  刘名光  梁新强
作者单位:广西医科大学附属肿瘤医院,
基金项目:广西区科委科技攻关课题 ( 9735 0 2 2 )
摘    要:目的:探讨黄芪抑制EB病毒(EBV)壳抗原在体外细胞中表达的作用。方法:采用间接免疫酶法研究黄芪提取液对B95-8细胞壳抗原表达的抑制作用。结果:无毒性浓度的黄芪提取液对巴豆油。正丁酸联合激发的EB病毒壳抗原表达有明显抑制作用。抑制率随药物浓度增加而提高,结论:黄芪抑制EBV壳抗原表达效果好,有望在鼻咽癌预防方面起一定作用。

关 键 词:黄芪  EB病毒  壳抗原  细胞表达
修稿时间:2001年3月10日

INHIBITORY EFFECT OF THE ROOT OF MEMBRANOUS MILE VETCH ON THE EX PRESSION OF VIRAL CAPSID ANTIGEN OF EPSTEIN-BARR VIRUS IN B95-8 CELLS
Cui Ying,Kuang Guoquian,Yue Huifen,et al.INHIBITORY EFFECT OF THE ROOT OF MEMBRANOUS MILE VETCH ON THE EX PRESSION OF VIRAL CAPSID ANTIGEN OF EPSTEIN-BARR VIRUS IN B95-8 CELLS[J].Journal of Guangxi Medical University,2001,18(6):791-792.
Authors:Cui Ying  Kuang Guoquian  Yue Huifen  
Abstract:Objective:To evaluate inhibitory effect of the root of membranous mile vetch on the expression of viral capsid antigen of Epstein Barr virus in B 95 8 cells Methods:The influences of the root of membranous mile vetch on the expression of viral capsid antigen of Epstein Barr virus in B 95 8 cells were studied by indirect immunoenzyme Result:The expression of EBV capsid antigens was significantly inhibited by non cytotoxic doses of the root of membranous mile vetch and the inhibition was does dependent Conclusion:The root of membranous mile vetch markedly inhibit the expression of EBV capsid antigen in B 95 8 cells It may be used in the prevention of nasopharyngeal carcinoma
Keywords:the root of membrarous mile vetch  Epstein  Barr virus  viral capsid antigen (VCA)
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