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氯氮平与氯丙嗪对血沉影响的对照研究
引用本文:张衍军,徐喜云,田茂生,刘爱军,赵逢玉,孔令生,龚福敏,白常林,任显峰.氯氮平与氯丙嗪对血沉影响的对照研究[J].中国民康医学,1996(5).
作者姓名:张衍军  徐喜云  田茂生  刘爱军  赵逢玉  孔令生  龚福敏  白常林  任显峰
作者单位:山东省济宁市复退军人精神病院
摘    要:将入组的精神分裂症病人随机分为氯氮平组(观察组)和氯丙嗪组(对照组),对其血沉的变化情况进行了为期五周的对照研究。结果显示:氯氮平组20例,血沉异常15例,占75%;氯丙嗪21例,血沉异常1例,占4.8%。两组具有统计学显著差异(x=21.24,P<0.005)。血沉异常多于用药后一周达最高值,此后逐渐降低,多于第五周末降至正常。对其发生原因进行了讨论。

关 键 词:氯氮平,氯丙嗪,血沉

A Control Study of Clozapine andChlorpromazlne's Effect on Blood Sedimen-tation
Zhang Yan - Jun ,et. al.A Control Study of Clozapine andChlorpromazlne's Effect on Blood Sedimen-tation[J].medical journal of chinese peoples health,1996(5).
Authors:Zhang Yan - Jun  et al
Institution:Zhang Yan - Jun ;et. al
Abstract:e randomly divided the schizophrenic patientsinto clozapine group and chlorpromazine group andhave cornpared the changes of their blood sedimenta-tion for 5 weeks. The results showed that 15 of the20 cases (75 % ) in the clozapine group , and 1 of the21 cases (4. 8% ) in the chlopromazine group had ab-normal blood sedimentation ; which had statistic sig-nificance (X2= 21. 24 , p <0. 005). Most of the ab-normal blood sedimentation reached the highest val-ue in a week after the medication , and then gradual-ly decreased, till normal by the end of the 5thweek.
Keywords:clozapine  chlorpromazine  blood sedimentation  
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