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β高效氯氰菊酯对雄性小鼠精子运动的影响
引用本文:张晓岚,;崔新刚,;崔新宇.β高效氯氰菊酯对雄性小鼠精子运动的影响[J].中国民康医学,2014(12):1-2.
作者姓名:张晓岚  ;崔新刚  ;崔新宇
作者单位:[1]牡丹江市卫生学校,黑龙江牡丹江157000; [2]牡丹江医学院公卫学院,黑龙江牡丹江157000;
基金项目:黑龙江省卫生厅资助项目(2011-287),牡丹江医学院科研项目(2010-24).
摘    要:目的:探讨高效氯氰菊酯对雄性小鼠精子运动的影响。方法:择体重为2535g健康清洁级小鼠60只,随机分为6组,每组10只,设高、中、低三个剂量组,溶剂组、空白对照组(生理盐水)和环磷酰胺阳性对照组。除环磷酰胺阳性对照组小鼠外,其余各组小鼠均按0.2ml/10g灌胃给药5d,于染毒后7d、14d分两批处死,用40倍光镜下计数精子快速直线运动、慢呆直线运动,非向前运动,不动精子数量,每只小鼠计数完整的精子1 000条。结果:本次实验结果显示染毒14d后各实验组小鼠间精子快速、慢呆直线运动、非向前运动,不动比率,差别有统计学意义。结论:高效氯氰菊酯对小鼠精子的运动能力有影响。

关 键 词:高效氯氰菊酯  小鼠  精子运动

Effects of beta-cypermethrin on male mice sperm motility
Institution:ZHANG Xiao-lan, CUI Xin-gang, CUI Xin-yu (1. Mudanjiang Medical School, Heilongjiang 157000, China; 2. School of Public Health of Mudanjiang Medical University)
Abstract:Objective:To discuss effects of beta-cypermethrin on male mice sperm motility. Methods:60 g healthy ICR mice with the body weight of 25-35g were randomly divided into 6 groups: high, medium and low three dose groups, solvent group, blank control group (normal saline) and cyclophosphamide positive control group. Except cyclophosphamide positive control group, the other groups were given the drug at 0. 2ml/ 10g by gavage for 5 days, then killed 7d and 14d after the exposure. Through 40× light micro-scope, the numbers of sperm fast motion, slow motion to stay straight, non-moving forward, not moving sperm were recorded, and 1000 complete sperms of a mouse were involved. Results: This experiment showed that the difference of sperm fast motion, slow motion to stay straight, non-moving forward, not moving sperm among the six groups were statistically significant. Conclusions: Beta-cyper-methrin has effects on the sperm ability of the mice.
Keywords:Beta-cypermethrin  Mouse  Sperm motility
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