高血压患者生存质量评价

目的 探讨高血压患者生存质量（QOL）。方法采用世界卫生组织QOL（WHOQOL）-100量表，对319例高血压患者和正常对照人群进行生存质量测量，比较病例组与对照组的生存质量差异。结果高血压患者生存质量在身体机能、心理状况、独立能力、社会关系、生活环境、个人信仰各领域及QOL-100总评分方面皆显著低于正常对照组人群（P〈0．01）；调整了其他疾病的混杂作用后，除个人信仰领域外，高血压患者其他各领域及QOL-100总评分方面仍皆低于对照组（P〈0．01）。Hotelling T2检验及多元方差分析显示，高血压患者与对照组人群的生存质量从6个领域综合来看，具有显著性差异（P〈0．01）。结论在有效降压的同时，积极改善患者的生存质量是临床抗高血压治疗的基本目标。

Evaluation of quality of life of hypertensive patients

OBJECTIVE: To evaluate the quality of life (QOL) of patients with hypertension. METHODS: Totally 319 patients with hypertension were investigated for their QOL in comparison with 319 healthy controls using the World Health Organization Quality of Life assessment instrument (WHOQOL-100). RESULTS: The scores of physical functions, psychological condition, independent ability, social relation, living environment, and personal faith and the total score of QOL-100 were significantly lower in the hypertensive patients than in the normal subjects (P<0.01). After adjusting the confounding factors of other diseases, the scores of all the items with the exception of personal faith and the total score of QOL-100 were all lower in the patients than in the controls (P<0.01). Hostelling T2 test and multivariate analysis of variance showed significant differences in the QOL between the hypertensive patients and the controls in the 6 domains synthesized (P<0.01), further demonstrating lowered QOL of hypertensive patients in comparison with the healthy population. CONCLUSION: Improvement of the hypertensive patients' QOL in addition to effective blood pressure control is a basic target in clinical therapy of hypertension.