针刺百会、水沟、神门穴对血管性痴呆患者豆状核葡萄糖代谢的影响

目的观察针刺后百会、水沟、神门血管性痴呆（VD）患者豆状核葡萄糖代谢的变化，探讨该穴组对豆状核功能的影响。方法将10例VD病人随机均分为2组。对照组治以针对偏瘫的常规穴位（手足三阳经为主），治疗组加用百会、水沟、神门。治疗前后所有病人均接受正电子发射型计算机断层显像（PET）检测葡萄糖代谢水平。以VD患者双侧豆状、核为感兴趣区，检测其治疗前后葡萄糖代谢水平并进行比较。结果治疗组健脑豆状核葡萄糖代谢有显著提高；对照组双侧豆状核葡萄糖代谢均无明显变化：结论针刺百会、水沟、神门治疗VD的机制与其提高豆状核葡萄糖代谢有关。

Effects of needling in Baihui (DU20), Shuigou (DU26) and Shenmen (HT7) on glucose metabolism in the lentiform nucleus in patients with vascular dementia]

OBJECTIVE: To observe the effect of needling in Baihui (DU20), Shuigou (DU26) and Shenmen (HT7) on glucose metabolism in the lentiform nucleus in patients with vascular dementia. METHODS: Ten patients with vascular dementia were randomized equally into control group to receive the treatment of needling in the routine acupoints for hemiplegia (chosen from 6 Yang meridians of hand and foot) and treatment group with needling in 3 additional acupoints of Baihui (DU20), Shuigou (DU26) and Shenmen (HT7) for dementia. All the patients were examined by positron emission tomography (PET) to detect glucose metabolism in the bilateral lentiform nuclei before and after treatment. RESULTS: Glucose metabolism in the lentiform nucleus in normal lateral brain was obviously enhanced in the treatment group, but not in the bilateral lentiform nuclei in the control group after treatment. CONCLUSION: The effect of needling in Baihui (DU20), Shuigou (DU26) and Shenmen (HT7) for treatment of vascular dementia may involve the enhancement of glucose metabolism in the lentiform nucleus.