川芎嗪及复方丹参注射液辅助治疗妊娠高血压综合征60例临床分析

目的 比较川芎嗪注射液及复方丹参注射液在辅助治疗妊娠高血压综合征(PHI)中的作用，探讨两药在改善微循环及胎儿宫内缺氧方面的差异，进一步指导临床用药。方法 选取2001年6月～2002年6月在我院住院治疗的60例PHI患者，平均分为2组，在有效镇静、解痉、降压、低流量吸氧等治疗的基础上，分别给予静脉滴注川芎嗪注射液及复方丹参注射液治疗1个疗程。结果 川芎嗪组抑制纤溶、改善微循环的效果显著；复方丹参组主要降低血液粘稠度、降低胆圊醇及血酯。结论 川芎嗪及复方丹参对PHI有肯定的治疗作用，由于两药的临床作用不同，需有针对性用药。

Ligustrazine and Salvia miltiorrhiza injection solution in complementary therapy of pregnancy-induced hypertension: clinical analysis of 60 cases]

OBJECTIVE: To compare the clinical effects of ligustrazine and Salvia miltiorrhiza injection solutions in the complementary therapy of pregnancy-induced hypertension (PIH). METHODS: Sixty patients with PIH were equally divided into 2 groups to receive intravenous infusion of 80 mg ligustrazine and 16 ml Salvia miltiorrhiza injection solution respectively, in addition to the conventional therapies. The effects of the two complementary treatments were compared. RESULTS: After a treatment course of 10 days, ligustrazine produced obvious effect in inhibiting fibrinolysis and promoting microcirculation of the patients. Salvia miltiorrhiza injection resulted in obvious reduction of blood viscosity, cholesterol and lipoprotein. CONCLUSION: Ligustrazine and Salvia miltiorrhiza injections produce obvious therapeutic effects on PIH, but they are used for different clinical purposes as their in pharmacological action difference.