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癌性贫血患者血清促红细胞生成素的检测及临床意义
引用本文:李黎波,罗荣城.癌性贫血患者血清促红细胞生成素的检测及临床意义[J].第一军医大学学报,2003,23(9):954-955.
作者姓名:李黎波  罗荣城
摘    要:目的 反复多次化疗的晚期肿瘤患者的癌性贫血是临床上治疗的难点,通过分析这些患者的血清促红细胞生成素(EPO)的水平,指导临床治疗以提高患者的生存质量。方法 对38例癌性贫血患者用ELISA进行血浆EPO的检测。结果 24例患者血浆:EPO高于正常值,仅l例低于正常值。讨论EPO是调节哺乳动物红细胞生成的主要因子。晚期癌性贫血患者的EPO血清水平正常或高于正常,说明机体的自身调整功能强大,对于临床治疗上EPO的应用有重要的指导意义。

关 键 词:癌性贫血  促红细胞生成素  检测  临床意义  治疗

Clinical significance of serum erythropoietin detection in patients with cancer-related anemia]
Li-bo Li,Rong-cheng Luo.Clinical significance of serum erythropoietin detection in patients with cancer-related anemia][J].Journal of First Military Medical University,2003,23(9):954-955.
Authors:Li-bo Li  Rong-cheng Luo
Institution:Department of Oncology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China. libo@fimmu.com
Abstract:OBJECTIVE: To explore the clinical significance of serum erythropoietin (EPO) detection in patients with cancer-related anemia for improving the life quality of the cancer patients in advanced stage with repeated chemotherapy. METHOD: The serum EPO levels were determined in 38 cases of cancer-related anemia with enzyme-linked immunosorbent assay (ELISA). RESULTS: In 24 patients, the serum EPO level was elevated above the normal range, and lowered EPO level was detected in only 1 cases. CONCLUSION: Normal or elevated serum EPO level in patients with cancer-related anemia indicates strong abilities of the patients in self regulation, having important clinical implications for the use of EPO.
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