糖络宁治疗糖尿病周围神经病变临床观察

符合选例标准的糖尿病周围神经病变患者134例，随机分为2组。治疗组采用益气养阴、化瘀通络的中药糖络宁口服液，对照组服用成药济生肾气丸。观察项目包括空腹及餐后2h血糖、糖基化血红蛋白、血液流变学指标、红细胞山梨醇、右腓总神经感觉传导速度、左尺神经运动传导速度，以及临床症状改善情况和药物不良反应。结果表明，经1个疗程治疗后，治疗组显效率55．88％，总有效率为93．14％，对照组显效率21．86％，总有效率为59．37％，组间比较差异显著（P＜0．05）；糖络宁对本病主要症状肢体麻木、肢体疼痛、肌力减退等的改善优于济生肾气丸，并能不同程度地改善上述实验室检测指标，且无任何毒副作用。

Clinical Observation on Patients of Diabetic Peripheral Nervous Lesion Treated with Tangluoning Oral Solution

134 Patients of diabetic peripheral nervous lesion were randomly divided into treating group treated with Tangluoning Oral Solution (TOS). and control group treated with Jisheng Shenqi Pills (JSP). After 1course of treatment, the results showed that the marked effective rate of the treating group was 55.88% and theoverall effective rate was 93.14 %; the marked effective rate of the control group was 21.86% and the overall effective rate was 59.37%; and difference between the two groups was significant (P<0.05). The results also showedthat TOS was better than JSP in reducing the symptoms such as limb numbness, melagra and muscular weakness;and TOS could, in different degrees, normalize certain laboratory criteria used in clinical observation on the diseaseswithout any toxic and side effects.