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血瘀证模型大鼠舌象评价标准研究
引用本文:尹军祥,田金洲,王永炎,时晶,李乐军,任映,宋崇顺,胡泉,杨金铎.血瘀证模型大鼠舌象评价标准研究[J].北京中医药大学学报,2007,30(8):529-531,插2.
作者姓名:尹军祥  田金洲  王永炎  时晶  李乐军  任映  宋崇顺  胡泉  杨金铎
作者单位:1. 北京中医药大学老年医学研究所,北京,100700
2. 中国中医科学院
基金项目:国家重点基础研究发展计划(973计划)资助项目(No.2003CB517104)
摘    要:目的通过模型动物舌体颜色及其光泽度的变化,判定血瘀证并建立血瘀证动物模型评价标准。方法40只SD大鼠随机分为5组,正常大鼠、寒凝血瘀证模型大鼠、肾上腺素皮下注射致血瘀证模型大鼠、10%大分子右旋糖苷尾静脉注射致血瘀证模型大鼠,采用数码相机拍摄舌象,分析比较所有舌腹面色泽深浅和舌下脉络呈色长短。结果舌腹面色泽深浅分级如下:舌质色泽红润记0分;舌质色泽红润略暗记1分;舌质色泽紫暗记2分;舌质色泽紫黑记3分。舌腹面舌下脉络色泽与长短分级如下:舌下脉络色泽红润,显色约1/3舌体长,记0分;舌下脉络色泽紫暗,显色大于1/3小于1/2舌体长,记1分;舌下脉络色泽紫暗,显色约1/2舌体长,记2分;舌下脉络色泽紫黑,显色约2/3舌体长,记3分。结论建立了血瘀证模型动物舌体色泽和舌下脉络的半定量评价标准,为血瘀证和活血化瘀药物的客观化研究提供了科学依据。

关 键 词:血瘀证  舌象  标准  大鼠
修稿时间:2006年5月26日

Evaluation criterion of tongue appearances in rat model of syndrome of blood stasis
YIN Jun-xiang,TIAN Jin-zhou#,WANG Yong-yan,et al..Evaluation criterion of tongue appearances in rat model of syndrome of blood stasis[J].Journal of Beijing University of Traditional Chinese Medicine,2007,30(8):529-531,插2.
Authors:YIN Jun-xiang  TIAN Jin-zhou#  WANG Yong-yan  
Institution:YIN Jun-xiang1,TIAN Jin-zhou1#,WANG Yong-yan2,et al.
Abstract:Objective To determine the syndrome of blood stasis to establish the evaluation criterion of animal model of blood stasis syndrome through the observation on color and luster changes of tongue body in the animal model.Methods All 40 SD rats were divided into 5 groups: the normal rats,rats with blood stasis syndrome induced by congealing cold,rats with blood stasis syndrome induced by hypodermic injection of adrenaline,rats with blood stasis syndrome induced by intravenous injection of 10% macromolecule dextran.The tongue pictures of all rats were taken with digital camera,and then the color and luster changes of tongue ventral surface and the coloration length of sublingual vein were compared and analyzed.Results The color and luster changes of tongue ventral surface were scored as follows: it was scored 0 if the texture of tongue was ruddy;it was scored 1 if the texture of tongue was ruddy and dim;it was scored 2 if the texture of tongue was purple;it was scored 3 if the texture of tongue was purple and dark.The color and luster changes and coloration length of sublingual vein were scored as follows: it was scored 0 if the color and luster was ruddy and the coloration length of sublingual vein was about one third of whole body of tongue;it was scored 1 if the color and luster was purple and the coloration length of sublingual vein was between one third and one second of whole body of tongue;it was scored 2 if the color and luster was purple and the coloration length of sublingual vein was about one second of whole body of tongue;it was scored 3 if the color and luster was purple and dark,the coloration length of sublingual vein was about two thirds of whole body of tongue.Conclusion A semiquantitative evaluation criterion for the color and luster changes of tongue and sublingual vein in model animals with blood stasis syndrome is established,which provides the scientific evidence for the objective research on blood stasis syndrome and Chinese medications with the effects of activating blood circulation and eliminating stasis.
Keywords:syndrome of blood stasis  tongue appearances  criterion  rats
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