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从中医络病与病络理论认识肿瘤血管生成
引用本文:奚胜艳,高学敏,张建军,张前.从中医络病与病络理论认识肿瘤血管生成[J].北京中医药大学学报,2008,31(12).
作者姓名:奚胜艳  高学敏  张建军  张前
作者单位:北京中医药大学基础医学院,北京,100029;北京中医药大学基础医学院,北京,100029;北京中医药大学基础医学院,北京,100029;北京中医药大学基础医学院,北京,100029
基金项目:国家自然科学基金资助项目  
摘    要:通过对肿瘤血管生成及络病相关理论的阐释,说明西医学肿瘤发生发展的重要理论--肿瘤血管生成与中医学络病、病络存在一定的相关性;肿瘤血管生成是一种病理机制,相当于中医学的"络道亢进",归属"病络";指出病络、络病理论对抗肿瘤血管生成的诸多借鉴作用,如针对"久病入络""新病入络"的中医治则与治法可为各种实体肿瘤所用,发挥阻抑络脉生成、清除络脉癌毒效能;并探讨了病络、络病理论对抗肿瘤血管生成中药筛选与研究的指导价值,以期为中医学对肿瘤的深入认识以及从络病、病络论治提供新的思路.

关 键 词:肿瘤  肿瘤血管生成  络病  病络  络道亢进  理论探讨

Recognition of tumor angiogenesis based on TCM theory of collateral diseases and abnormal collaterals
XI Sheng-yan,GAO Xue-min,ZHANG Jian-jun,ZHANG Qian.Recognition of tumor angiogenesis based on TCM theory of collateral diseases and abnormal collaterals[J].Journal of Beijing University of Traditional Chinese Medicine,2008,31(12).
Authors:XI Sheng-yan  GAO Xue-min  ZHANG Jian-jun  ZHANG Qian
Abstract:To illustrate the correlation between tumor angiogenesis,that is an important theory about tumor development in modern medicine,and collateral diseases or abnormal collaterals in TCM theory through expounding the theory related to tumor angiogenesis and abnormal collaterals.The tumor angiogenesis was considered as a kind of pathogenesis,which was corresponded to "collateral accentuation" in TCM theory and belonged to abnormal collaterals.The reference of the theory of collateral diseases and abnormal collaterals for anti-angiogenesis was pointed out,for example,the therapeutic principles and methods for "chronic diseases intruding into collaterals" and "new diseases intruding into collaterals" can be used for various solid tumors to inhibit angiogenesis and cleanup cancer toxin in collaterals.The value of screening of Chinese herbal drugs with the effects of anti-angiogenesis was discussed to open a new think train for understanding tumors by TCM theory and curing tumors based on TCM theory of collateral diseases or abnormal collaterals.
Keywords:tumor  tumor angiogenesis  collateral diseases  abnormal collaterals  collateral accentuation  theoretical probing
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