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| 乌司他丁对体外循环术中肺脏的保护作用 | |
| 引用本文： | 杨文凯,龚南平,杨春丽,王文英,杨升萍.乌司他丁对体外循环术中肺脏的保护作用[J].中国体外循环杂志,2010,8(1):37-38. |
| 作者姓名： | 杨文凯 龚南平 杨春丽 王文英 杨升萍 |
| 作者单位： | 1. 江西省人民医院心胸外科,南昌,330006 2. 江西省人民医院ICU,南昌,330006 3. 江西省人民医院手术室,南昌,330006 |
| 基金项目： | 2006年江西省卫生厅课题 |
| 摘 要： | 目的研究乌司他丁对体外循环术中肺脏的保护作用。方法选择心脏直视手术患者60例,分别设乌司他丁治疗组和对照组各30例,在5个时间点分别检测中性粒细胞弹性酶(NE)、白介素(IL)-8、超氧化物歧化酶(SOD)含量的变化。结果在主动脉开放后的3个时间点两组数据具有显著性差异。结论乌司他丁在体外循环中具有抗蛋白酶分解、调节细胞因子和减少氧自由基的肺保护作用。 |
| 关 键 词： | 乌司他丁 体外循环 肺保护 |
The lung protective effect of Ulinastatin during extracorporeal circulation |
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| Yang Wen-kai,Gong Nan-ping,Yang Chun-li,Wang Wen-ying,Yang Sheng-ping.The lung protective effect of Ulinastatin during extracorporeal circulation[J].Chinese Journal of Extracorporeal Circulation,2010,8(1):37-38. | |
| Authors: | Yang Wen-kai Gong Nan-ping Yang Chun-li Wang Wen-ying Yang Sheng-ping |
| Institution: | Yang Wen-kai,Gong Nan-ping,Yang Chun-li,Wang Wen-ying,Yang Sheng-ping Department of Cardiothoracic Surgery,Jiangxi Province People Hospital,Jiangxi Nanchang,330006,China |
| Abstract: | OBJECTIVE To research the lung protective effect of Ulinastatin during extracorporeal circulation （ECC）. METHODS 60 patients undergoing open -heart surgery with ECC divide into two groups equally： Ulinastatin group and control group. NE.IL -8 and SOD＇levels were determined on 5 time points in each group. RESULTS The two groups had significant difference on 3 time points after opening aorta. CONCLUSION Ulinastatin has the ability of lung protective effect during ECC in three crucial aspects. |
| Keywords: | Ulinastatin Extracorporeal circulationn Lung protectio |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |