| 牛蒡子化学成分研究 |
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| 引用本文： | 冉小库,窦德强.牛蒡子化学成分研究[J].辽宁中医学院学报,2013(7):71-72. |
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| 作者姓名： | 冉小库 窦德强 |
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| 作者单位： | 辽宁中医药大学药学院,辽宁大连116600 |
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| 基金项目： | 沈阳市科技局计划项目（F11-264-1-20） |
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| 摘 要： | 目的：研究牛蒡子的化学成分。方法：利用各种色谱技术进行分离、纯化,通过波谱解析结合理化性质鉴定化合物的结构。结果：从牛蒡子中分离得到6个单体化合物,根据理化性质和光谱数据分别鉴定为牛蒡子苷元（1）、拉帕酚B（2）、拉帕酚F（3）、拉帕酚C（4）、牛蒡子苷（5）、3,5-二咖啡酰基奎宁酸（6）。结论：3,5-二咖啡酰基奎宁酸（6）为首次从该植物中分离得到。
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| 关 键 词： | 牛蒡 化学成分 木脂素 3 5-二咖啡酰基奎宁酸 |
Studies on Chemical Constituents of Arctium Lappa L. |
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| RAN Xiaoku,DOU Deqiang.Studies on Chemical Constituents of Arctium Lappa L.[J].Journal of Liaoning College of Traditional Chinese Medicine,2013(7):71-72. |
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| Authors: | RAN Xiaoku DOU Deqiang |
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| Institution: | ( College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, Liaoning, China ) |
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| Abstract: | Objective： To investigate the chemical constituents from Arctium lappa L. Methods： The extracts of Arctium lappa L were submitted to a combination of chromatographic materials, silica gel, ODS column chromatography and finally preparative HPLC was used to obtain six compounds. Results： Six compounds were obtained, and their structures were identified as （ - ）-aretigenin （ 1 ）, lappaol B （ 2 ）, lappaol F （ 3 ）, lappaol C （ 4 ）, aretiin （ 5 ）, 3,5-dicaffeoylqunic acid （ 6 ）. Conclusion ： 3,5-dieaffeoylqunic acid was isolated from this plant for the first time. |
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| Keywords: | Arctium lappa L chemical consitituent lignans 3 5-dicaffeoylqunic acid |
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