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幽门螺杆菌根除对儿童急性特发性血小板减少性紫癜的疗效
引用本文:李朝霞,刘迪军,潘春球,桑显富,李旭.幽门螺杆菌根除对儿童急性特发性血小板减少性紫癜的疗效[J].南方医科大学学报,2009,29(6):1243.
作者姓名:李朝霞  刘迪军  潘春球  桑显富  李旭
作者单位:1. 湖南岳阳市二医院儿科,湖南,岳阳,414000
2. 南方医科大学南方医院急诊科,广东,广州,510515
摘    要:目的 观察幽门螺杆菌(Hp)根除治疗对常规视治的轻度儿童急性特发性血小板减少性紫癜(ITP)的疗效.方法 血清Hp阳性的急性ITP初治患儿93例被随机分为治疗组(A组51例)和对照组(B组42例).B组行常规激素治疗,A组在此基础上加根除Hp治疗.结果 A组Hp清除率87.5%;两组间近期疗效无显著性差异,但1年内复发率A组低于B组(P=0.033).结论 Hp清除对儿童急性ITP的疗效无影响,但能减少复发率,对于Hp感染的ITP患儿建议行根除Hp治疗.

关 键 词:特发性血小板减少性紫癜  幽门螺旋杆菌  激素治疗

Effect of Helicobacter pylori eradication on childhood acute idiopathic thrombocytopenic purpura
LI Chao-xia,LIU Di-ju,PAN Chun-qiu,SANG Xian-fu,LI Xu.Effect of Helicobacter pylori eradication on childhood acute idiopathic thrombocytopenic purpura[J].Journal of Southern Medical University,2009,29(6):1243.
Authors:LI Chao-xia  LIU Di-ju  PAN Chun-qiu  SANG Xian-fu  LI Xu
Institution:LI Chao-xia1,LIU Di-jun2,PAN Chun-qiu2,SANG Xian-fu2,LI Xu2 1Department of Pediatrics,Second Hospital of Yueyang City,Yueyang 414000,China,2Emergency Department,Nanfang Hospital,Sothern Medical University,Guangzhou 510515
Abstract:Objective To evaluate the effect of Helicobacter pylor (Hp) eradication in children with acute idiopathic thrombocytopenic purpura (ITP). Methods Ninety-three children with acute ITP and Hp infection were divided into two groups and treated with prednisone and Hp eradication (group A, 51cases) or with prednisone without Hp eradication (group B, 42 cases). Results The Hp eradiation rate was 94.1% in group A. No difference was found in the therapeutic effects on IPT between the two groups, but the recurrence ...
Keywords:idiopathic thrombocytopenic purpura  Helicobacter pylori  
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