2型糖尿病合并高尿酸血症的相关因素分析

目的研究2型糖尿病高尿酸血症的临床特征。方法选择1040例2型糖尿病患者，分成糖尿病高尿酸血症和糖尿病正常尿酸血症组，测定并比较两组的血肌酐(Cr)、血糖(FPG)、血压(BP)、血胆固醇(CHO)、三酰甘油(TG)、体重指数(BMI)、空腹血浆胰岛素(FINS)水平。结果2型糖尿病高尿酸血症组的Cr、BP、TG、BMI、FINS、HOMA指数高于对照组；Logistic回归分析表明舒张压、TG、Cr是2型糖尿病高尿酸的危险因素。结论2型糖尿病高尿酸血症发生高血压、高脂血症、肾功能不全比例高，更具有胰岛素抵抗倾向。

Analysis of the Factors Related to Serum Uric Acid in Patients with Type 2 Diabetes Mellitus

Purpose To investigate the clinic characteristic of hyperuricemia in type 2 diabetes mellitus. Methods One thousand forty cases were divided into two groups according to their serum uric acid level. Fasting glucose(FPG) ,creatinin(Cr) ,cholesterol(CHO) , triglyceride(TG) ,blood pressure(BP) ,body mass index(BMI), fasting serum insulin(FINS) were measured and compared between the groups. Results Patients with hyperu-ricemia in type 2 diabetes had markedly higher BP, TG,Cr,BMI,FINS and HOMA-IR index than those with normal serum uric acid. Logistic regression analysis results suggested that DBP,TG,Cr were the independent risk factors of hyperuricemia in type 2 diabetes. Conclusions Patients with hyperuricemia in type 2 diabetes had a higer prevalence of hypertension, hypertriglyceridermia and dysfunction of renal;had a more tendency to insulin resistance.