首页 | 本学科首页   官方微博 | 高级检索  
检索        

乳腺癌新辅助化疗的研究进展
引用本文:沈雷.乳腺癌新辅助化疗的研究进展[J].复旦学报(医学版),2016,43(2):244.
作者姓名:沈雷
作者单位:复旦大学附属中山医院普外科 上海 200032
基金项目:上海市科学技术委员会科研计划项目 (14411950302)
摘    要: 近年,乳腺癌新辅助化疗的研究不再局限于局部晚期乳腺癌、炎性乳腺癌或肿块较大不可保乳的乳腺癌患者,研究的范围进一步扩大到可手术的早期乳腺癌,这得益于进一步认识到新辅助化疗的优势。新辅助化疗不仅提高了保乳率,更便于了解患者对化疗方案的敏感性,甚至预测患者的预后,从而指导临床化疗方案的调整。本文将对新辅助化疗药物的选择、疗程及用法等方面进行总结,同时对病理完全缓解的定义、预后意义与分子分型的关系等内容进行探讨。

关 键 词:乳腺癌  新辅助化疗  化疗方案  病理完全缓解
收稿时间:2015-07-03

Advances in neoadjuvant chemotherapy for breast cancer
SHEN Lei,ZHANG Hong-wei.Advances in neoadjuvant chemotherapy for breast cancer[J].Fudan University Journal of Medical Sciences,2016,43(2):244.
Authors:SHEN Lei  ZHANG Hong-wei
Institution:Department of General Surgery,Zhongshan Hospital,Fudan University,Shanghai 200032,China
Abstract:In recent years,studies of neo-adjuvant chemotherapy for breast cancer was not limited to locally advanced breast cancer,inflammatory breast cancer,or larger mass breast cancer which cannot receive breast-conserving surgery.Studies range has been further expanded to the operable early breast cancer.Thanks to a greater public awareness of the advantages of neo-adjuvant chemotherapy,it has improved the rate of breast conservation,given a better understanding of patient’s sensitivity to chemotherapy,even can predict the prognosis of patients.Therefore,it provides guidance for adjustment of clinical chemotherapy.This review summarizes the selection of drugs,courses and intensive therapy in neo-adjuvant chemotherapy for breast cancer.Meanwhile,the definition of pathologic complete remission (pCR),prognostic significance and its correlation with molecular typing etc.are further discussed.
Keywords:breast cancer  neoadjuvant chemotherapy  chemotherapy regimens  pathologic complete response
点击此处可从《复旦学报(医学版)》浏览原始摘要信息
点击此处可从《复旦学报(医学版)》下载免费的PDF全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号