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社区高血压人群抗高血压药物的利用情况、依从性及影响因素
引用本文:杜文民,王永铭,陈斌艳,范维琥,耿晓芳.社区高血压人群抗高血压药物的利用情况、依从性及影响因素[J].复旦学报(医学版),2001,28(5):425-428.
作者姓名:杜文民  王永铭  陈斌艳  范维琥  耿晓芳
作者单位:1. 复旦大学药学院药理学教研室,
2. 复旦大学附属华山医院心内科,
3. 上海市华东医院临床药理室,
摘    要:目的 了解实际自然人群中抗高血压药物的分布和使用情况。方法 利用抗高血压药物的用药监测系统,统计高血压人群中各类抗高血压药物的使用情况和依从性;对依从性的影响因素进行非条件logistic回归分析。结果 社区高血压病有2522例,未用药539例(占21.37%),不规则服药1059例(占41.99%),规则服药924例(占36.64%),(单一服药375例,联合服药549例);单独服用复方降压片173例,单独服用硝苯地平108例,单独服用其他药物94例;复方降压片与硝苯地平联合服用(复方降压片+硝苯地平)252例,卡托普利与硝苯地平联合服用(卡托普利+硝苯地平)132例,其他联合用药165例。结论 社区人群抗高血压药物服药依从性低。吸烟、心脑血管病是主要不规则服药的独立危险因素;知识得分、非药物治疗、发病时间长是主要不规则服药的独立保护因素;吸烟、心脑血管病是主要未服药的独立危险因素;知识得分高、非药物治疗、发病时间长、有经济来源是主要未服药的独立保护因素。

关 键 词:抗高血压药物  药物利用  药物依从性  logistic回归  高血压
修稿时间:2001年3月2日

Antihypertensive Drugs Utilization, Compliance and Influence Factors of Hypertensive Population in Community
Abstract:Purpose To know antihypertensive drugs utilization,compliance and influence factors of hypertensive population in community. Methods Using a drug monitor system in hypertensive crowd,we investigated the utilization and compliance of antihypertensive drugs in hypertensive population,and analyses influence factors in logistic regression. Results The number of not taking medicine is 539(21.37%),the number of taking medicine irregularly is 1 059(41.99%),and the number of taking medicine regularly is 924(36.64%). Conclusions The compliance of antihypertensive drugs in hypertensive population is low.Smoking,cardiovascular diseases are independent dangerous factors of not taking medicine.High score of knowledge,non-pharmacological treatment,years when have been ill are long,have income are independent protective factors of not taking medicine.Smoking,cardiovascular diseases are independence dangerous factors of taking medicine irregularly.High score of knowledge,non pharmacological treatment,years when have been ill are long are independence protective factors of taking medicine irregularly.
Keywords:antigypertensive drug  drug utilization  compliance  logistic regression
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