| 胃动脉内化疗灌注及其栓塞术的COX生存模型分析 |
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| 引用本文： | 王小林,李茂全,陈英.胃动脉内化疗灌注及其栓塞术的COX生存模型分析[J].复旦学报(医学版),1993(6). |
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| 作者姓名： | 王小林 李茂全 陈英 |
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| 作者单位： | 上海医科大学中山医院放射科
(王小林，李茂全)，公共卫生学院卫生统计学教研室(陈英) |
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| 基金项目： | 上海医科大学校科研基金 |
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| 摘 要： | 对54例晚期胃癌患者施行胃动脉内化疗灌注(GAI)或胃动脉内化疗栓塞(GAE)术,采用COX生存模型对晚期胃癌患者作GAI或GAE后的生存情况进行分析。结果提示:GAE组(35例)患者的生存概率随时间推移变化不大,基本保持在85％以上,而GAI组(19例)患者的生存概率降至40、72％,GAE组与GAI组的两个治疗方案比较P<0.001,有极显著差异。影响生存期的因素还包括:年龄对生存的影响(P<0.0385);化疗方案对生存的影响等多因素比较均有极显著差异(P<0.001)。化疗方案(FAM和FCM)对生存的影响以间隔运用疗效最佳。
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| 关 键 词： | 胃癌 胃动脉内化疗灌注 胃动脉内化疗栓塞 COX生存模型 |
COX SURVIVAL MODEL ANALYSIS OF PATIENTS WITH LATE GASTRIC CANCER BY TREATED INTRAARTERIAL CHEMOTHERAPEUTIC INFUSION AND CHEMOEMBOLIZATION |
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| Wang Xiao-Lin,Li Mao-Quan,Chen Ying.COX SURVIVAL MODEL ANALYSIS OF PATIENTS WITH LATE GASTRIC CANCER BY TREATED INTRAARTERIAL CHEMOTHERAPEUTIC INFUSION AND CHEMOEMBOLIZATION[J].Fudan University Journal of Medical Sciences,1993(6). |
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| Authors: | Wang Xiao-Lin Li Mao-Quan Chen Ying |
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| Abstract: | 54 patients with late non-resectable gastric carcinoma were treated by chemotherapeutic infusion and chemoembolization, and analysed by the COX survival model. 85 cases were treated by chemoembolization, and 19 by chemotherapeutic infusion as a control group. Analysis shawe that age, treatment method, chemotherapeutic regime and pathological characteristics of the cancer tissue were'all factors aff ecting survival results. Multiple factor comparsion demonstrate obvious differences between the two treatment groups, and a greater effectiveness in patients treated bu the FAM + FGM method. |
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| Keywords: | gastric carcinoma intraarterial chemotherapeutic infusion in- traarterial chemotherapeutic embolization COX survival model |
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