| D-半乳糖致衰老动物模型的建立及其检测方法 |
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| 引用本文： | 朱亚珍,朱虹光.D-半乳糖致衰老动物模型的建立及其检测方法[J].复旦学报(医学版),2007,34(4):617-619. |
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| 作者姓名： | 朱亚珍 朱虹光 |
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| 作者单位： | 复旦大学上海医学院病理学教研室,上海,200032 |
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| 摘 要： | D-半乳糖衰老动物模型是由我国学者龚国清等在1991年构建的。与其它几种衰老动物模型如SAMP系小鼠衰老模型,臭氧损伤衰老模型,去胸腺衰老模型,自然衰老模型等相比,该模型简便易行,价格低廉,结果稳定,因而得到广泛运用。鉴于该模型近年来的运用和发展,且众文献中的检测指标各有侧重,本文拟对该模型构建方法和原理以及检测指标从行为学水平,生化水平,形态学水平,分子生物学水平等方面由浅入深进行综述。
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| 关 键 词： | D-半乳糖 衰老 动物模型 |
| 修稿时间： | 2006年9月14日 |
Establishment and measurement of D-galactose induced aging model |
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| ZHU Ya-zhen,ZHU Hong-guang.Establishment and measurement of D-galactose induced aging model[J].Fudan University Journal of Medical Sciences,2007,34(4):617-619. |
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| Authors: | ZHU Ya-zhen ZHU Hong-guang |
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| Abstract: | D-galactose induced aging model was established by a chinese scholar named Gong Guoqing in 1991.This aging model is convenient,cheap and stable so that it has been used widespreadly comparing with other aging models such as SAMP aging model,ozone induced aging model,thymus removed model,natural aging model and so on.Reviewing the application and development of D-galactose induced aging model,and different measurements in different records,we summarized the establishment and theory of D-galactose induced aging model,furthermore,we described the measurements from ethology,biochemistry,morphology and molecular biology in this review. |
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| Keywords: | D-galactose aging animal model |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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