Clinical and Pathological Studies on Severe Parathyroid Hyperplasia in Uremic Patients with Secondary Hyperparathyroidism |
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作者姓名: | SunB WangXY |
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作者单位: | DepartmentofNephrology,theFirstAffiliatedHospitalofNJMU,Nanjing210029 |
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摘 要: | Objective To evaluate clinical significance of parathyroid proliferation in secondary hyperpar athyroidism(SHPT).Methods The specimens of parathyroid were taken from 7 patients with SHPT and resistance to medical therapy.The histological sections were routinely stained with hematoxylin-eoxin(HE) stain,and according to macroscopical and microscopical examinations,divided into two types:diffuse type (D-type) with a normal lobular constitution and nodular type(N-type).The sum of parathyroid cells under HE stain were calculated by computer image analysis system.Results There was 16.1 times increase in the weight of parathyroid of CRF patients with SHPT and 1.86 times increase in sum of parathyroid cells.The proliferation of N-type parathyroid was especially noticeable.Conclusion We suggest that D-type hyperplasia parathryoid should be selected in autotransplantation,expecially quite small piece,in order to prevent symtom recurrence of SHPT.
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关 键 词: | 尿毒症 甲状旁腺机能亢进 甲状旁腺增生 临床 病理学 |
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