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Forty-two Patients with Takayasu Arteritis: Clinical,Laboratory and Angiographic Studies
作者姓名:刘晓华  刘嘉玲  庄振武  李麟荪
作者单位:Liu XiaohuaLiu Jialing Zhuang Zhenwu 1Li Linsun Department of Rheumatology,\ 1Department of Radiology,the First Affiliated Hospital,\= Nanjing Medical University,Nanjing 210029,P.R.China \=\=
摘    要:IntroductionTakayasuarteritisisachronicnonspecificandocclusiveinflammationofunknownetiologyafectingtheaortaanditsmajorbranche...


Fortytwo Patients with Takayasu Arteritis:\= Clinical, Laboratory and Angiographic Studies
Liu XiaohuaLiu Jialing Zhuang Zhenwu Li Linsun.Forty-two Patients with Takayasu Arteritis: Clinical,Laboratory and Angiographic Studies[J].Journal of Nanjing Medical University,1999(1).
Authors:Liu XiaohuaLiu Jialing Zhuang Zhenwu Li Linsun
Institution:Liu XiaohuaLiu Jialing Zhuang Zhenwu 1Li Linsun Department of Rheumatology,\ 1Department of Radiology,the First Affiliated Hospital,\= Nanjing Medical University,Nanjing 210029,P.R.China \=\=
Abstract:This study was to analyze 42 cases of Takayasu arteritis, and to discuss its early diagnosis and treatment. The clinical differentiation, conventional laboratory study, immunology test and angiography of 42 patients dispersed in 9 clinic departments were analyzed. The first symptoms of these patients were pulseless (21.4%) and secondary hypertension (78.6%) were found. The murmur could be heard in the area corresponding to the narrowed artery in 70%. Conventional laboratory study and immunology tests were not valuable. The sensitivity for arterial stenosis by Doppler color Bultrasonography and radioisotopic nephrography was about 80%. Angiography could show the type of brachiocephalic trunk 8 cases, renal 29 cases and widespread 5 cases. Eighteen cases were treated with angioplasty, and 14 of them were successful. Nine cases in early stage were treated with medicine, and 7 cases of them got remission. Early diagnosis still remains a key problem for further study. Antiendothelial cell antibodies (AE CA) and thrombomodulin are suggested as a helpful basis for early diagnosis. Angiography could explicate the degree of the lesions and indicate angioplasty for them, and should be adopted earlier.
Keywords:Takayasu arteritis  diagnosis  treatment  angiography
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