| 转化生长因子β_1在毛细血管瘤组织中的表达 |
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| 引用本文： | 袁新初,周乾毅.转化生长因子β_1在毛细血管瘤组织中的表达[J].武汉大学学报(医学版),2002,23(3):213-214. |
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| 作者姓名： | 袁新初 周乾毅 |
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| 作者单位： | 武汉科技大学医学院组织学与胚胎学教研室,武汉,430080 |
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| 摘 要： | 目的 :探讨TGF β1 在毛细血管瘤病理演变过程中的作用。方法 :通过免疫组织化学方法及图像分析技术 ,观察并分析TGF β1 在不同时期小儿皮肤毛细血管瘤组织中的表达变化。结果 :退化期血管瘤组织中TGF β1 表达阳性面积率及平均光密度明显高于增生期血管瘤组织 ,两者经统计学处理具有显著差异性 (P <0 .0 5 )。结论 :由此提示TGF β1 可能是影响小儿皮肤毛细血管瘤增生与退化的重要因素
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| 关 键 词： | 毛细血管瘤 转化生长因子β1 免疫组织化学 |
| 修稿时间： | 2001年9月24日 |
Expression of Transforming Growth Factor-β1 in Capillary Hemangioma |
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| Yuan Xinchu,Zhou Qianyi.Expression of Transforming Growth Factor-β1 in Capillary Hemangioma[J].Medical Journal of Wuhan University,2002,23(3):213-214. |
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| Authors: | Yuan Xinchu Zhou Qianyi |
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| Institution: | Yuan Xinchu,Zhou Qianyi Department of Histology and Embrylology,Medical College,Wuhan University of Science and Technology,Wuhan 430080,China |
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| Abstract: | Objective: To study the role of transforming growth factor Beta1(TGF β 1) in capillary hemangioma pathological development procession. Methods: The expression change of TGF β 1 in children skin hemangiomas different phase was tested by the immunohistochemical method and analysed by image analysis technique. Results: The area rate and average optical density of positive expression of TGF β 1 in involuted phase was obviously higher than that in proliferating phase. There were significant statistical differences between them (P<0.05). Conclusion: This finding suggest that TGF β 1 may be an important factor in hemangioma pathological development procession of proliferation and involution. |
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| Keywords: | capillary hemangioma transforming growth factor beta 1 immunohistochemical method |
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