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| 普通级、SPF级SD大鼠、Wistar大鼠血常规的测定与比较 | |
| 引用本文： | 詹纯列,肖育华,王露霞,陈凯锐,李权超,李新春,李建军,郑文岭.普通级、SPF级SD大鼠、Wistar大鼠血常规的测定与比较[J].广东医学,2002,23(10):1025-1026. |
| 作者姓名： | 詹纯列 肖育华 王露霞 陈凯锐 李权超 李新春 李建军 郑文岭 |
| 作者单位： | 1. 广州军区广州总医院,医学实验科,广州,510010 2. 广州军区广州总医院,检验科,广州,510010 3. 广州军区军事医学研究所,广州,510507 |
| 摘 要： | 目的 测定普通级、SPF级SD大鼠、Wistar大鼠血常规指标并进行比较。方法 Coulter -JT全自动血常规检测仪自动检测。结果 普通级、SPF级SD大鼠白细胞计数、红细胞计数、血红蛋白、血小板计数、血小板平均分布宽度、红细胞平均分布宽度相差非常显著 (P <0 0 1) ;中性粒细胞、单核细胞相差显著 (P <0 0 5 )。普通级、SPF级Wistar大鼠白细胞计数、中性粒细胞、单核细胞、红细胞计数、红细胞平均体积、平均红细胞血色素量相差非常显著 (P <0 0 1) ;血红蛋白、血小板计数、血小板平均分布宽度相差显著 (P <0 0 5 ) ,其他指标相差不显著。结论 不同微生物学环境对SD、Wistar大鼠血常规指标有较大影响 |
| 关 键 词： | 普通级 SPF级 血常规 动物实验 Coulter－JT全自动血常规检测仪 |
| 修稿时间： | 2002年6月17日 |
Comparison of normal values of blood routine examination in conventional,SPF SD and Wistar Rats |
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| Zhan Chunlie,Xiao Yuhua,Wang Luxia,et al..Comparison of normal values of blood routine examination in conventional,SPF SD and Wistar Rats[J].Guangdong Medical Journal,2002,23(10):1025-1026. | |
| Authors: | Zhan Chunlie Xiao Yuhua Wang Luxia |
| Institution: | Zhan Chunlie,Xiao Yuhua,Wang Luxia,et al. Department of Medical Research,General Hospital of Guangzhou Command of PLA,Guangzhou 510010 |
| Abstract: | Objective To measure and compare the normal values of blood routine examination in conventional,SPF SD and Wistar rat. Methods Coulter-JT was used to measure blood routine. Results The WBC,RBC,Hb,Plt,PDW and RDW in conventional and SPF SD rats had very significant difference( P <0 01),The difference of N and MONO was significant( P <0 05). The WBC,N,MONO,RBC,MCV,MCH in conventional and SPF wistar rats had very significant difference( P <0 01). The Hb,Plt,PDW had significant difference( P <0 05). Other pararnefers had no significant difference( P >0 05). Conclusion Different microbiological background significantly affects normal values of blood routine of rats. |
| Keywords: | Conventional SPF Rat Blood routine |
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