| 垂体泌乳素腺瘤患者溴隐亭耐药与血清PRL水平的关系 |
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| 引用本文： | 张湘衡,牟永告,赛克,杨群英,魏大年,蒋小兵,钟鸣谷,王振宁,陈忠平.垂体泌乳素腺瘤患者溴隐亭耐药与血清PRL水平的关系[J].广东医学,2011,32(3):306-308. |
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| 作者姓名： | 张湘衡 牟永告 赛克 杨群英 魏大年 蒋小兵 钟鸣谷 王振宁 陈忠平 |
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| 作者单位： | 中山大学肿瘤医院神经外科/神经肿瘤科 |
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| 基金项目： | 华南肿瘤学国家重点实验室基金 |
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| 摘 要： | 目的 了解在对溴隐亭耐药和有效的泌乳素腺瘤患者间,早期血清PRL水平是否存在差异.方法 收集了105例垂体泌乳素腺瘤患者的临床资料,根据溴隐亭疗效分为有效组和耐药组,其中有效组86例,耐药组19例.对两组患者药物治疗前血清PRL水平进行比较.结果 有效组中患者早期血清PRL水平为(689.4±136.9)μg/L高于耐...
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| 关 键 词： | 泌乳素腺瘤 溴隐亭 泌乳素 耐药 |
Correlation between resistance to bromocriptine and plasma prolactin level in patients with prolactinoma. |
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| ZHANG Xiang-heng,MU Yong-gao,SAI Ke,YANG Qun-ying,WEI Da-nian,JIANG Xiao-bing,ZHONG Ming-gu,WANG Zhen-ning,CHEN Zhong-ping.Correlation between resistance to bromocriptine and plasma prolactin level in patients with prolactinoma.[J].Guangdong Medical Journal,2011,32(3):306-308. |
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| Authors: | ZHANG Xiang-heng MU Yong-gao SAI Ke YANG Qun-ying WEI Da-nian JIANG Xiao-bing ZHONG Ming-gu WANG Zhen-ning CHEN Zhong-ping |
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| Institution: | ZHANG Xiang-heng,MU Yong-gao,SAI Ke,YANG Qun-ying,WEI Da-nian,JIANG Xiao-bing,ZHONG Ming-gu,WANG Zhen-ning,CHEN Zhong-ping.Department of Neurosurgery,Tumor Hospital,Sun Yat-sen University,Guangzhou 510060,China |
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| Abstract: | Objective To observe the relationships between resistance to bromocriptine and plasma prolactin level in patients with prolactinoma,so as to provide evidence for early diagnosis.Methods The clinical data of 105 patients with prolactinomas were collected.According the response to bromocriptine therapy,subjects were divided into bromocriptine-sensitive group(n=86) and bromocriptine-resistant group(n=19),respectively.The baseline plasma prolactin levels were analysed by t-test between the two groups.Results Si... |
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| Keywords: | prolactinoma bromocriptine prolactin resistance |
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