儿童单纯型过敏性紫癜与食物不耐受的相关性研究

摘要] 目的 探讨儿童单纯型过敏性紫癜与食物不耐受的相关性及不耐受食物禁食/轮替治疗对儿童单纯型过敏性紫癜的疗效。方法 采用ELISA法检测98例儿童单纯型过敏性紫癜患者血清食物过敏原IgG与IgE；将其中中重度食物不耐受患者，随机分为观察组（常规治疗+食物禁食/轮替疗法）与对照组（常规治疗），观察疗效。结果 受检患者血清食物过敏原IgG阳性率（98.0%）显著高于IgE阳性率（33.7%）（P<0.05）。所有患者中，有56例中重度食物不耐受。经过3个月治疗，观察组疗效(92.9%)显著优于对照组(67.9%) （P<0.05）。结论 食物不耐受与儿童单纯型过敏性紫癜有显著相关性，不耐受食物禁食/轮替治疗对儿童单纯型过敏性紫癜的治疗有一定作用。

The correlation research between food intolerance and child purpura simplex

Objective To explore the correlation of food intolerance and child purpura simplex.Method The level of IgG,IgE antibody to several foods in serum were determined in 98 children with purpura simplex by ELISA. Patients with moderate and severe food intolerance were randomly divided into treatment group (received routine therapy and food forbidden/alternative food therapy ) and control group(received routine therapy),and to observe the effectiveness after 3 months. Result The positive ratio of IgG antibody(98.0% )to foods in the children with purpura simplex were significantly higher than that of IgE（33.7%）P<0.05）. In all patients, there were 56 patients with moderate or severe foods intolerance. After three months , the effectiveness in treatment group(92.9%) were significantly higher than that of control group (67.9%)（P<0.05）. Conclusion There were significantly correlation between food intolerance and child purpura simplex. Food forbidden/alternative food therapy plays some role on the treatment of child purpura simplex.