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按揉委中穴对脑愉悦回路的影响
引用本文:李征宇,孙兮文,张效初,陈培青,沈雪勇,严隽陶.按揉委中穴对脑愉悦回路的影响[J].上海中医药大学学报,2008,22(4):51-53.
作者姓名:李征宇  孙兮文  张效初  陈培青  沈雪勇  严隽陶
作者单位:1. 上海中医药大学针灸推拿学院,上海,201203
2. 上海华东医院磁共振室,上海,200040
3. 中国科技大学生命科学院,安徽,合肥,2300341
4. 上海中医药大学附属岳阳中西医结合医院,上海,200437
摘    要:目的:观察按揉委中穴对脑愉悦回路的影响。方法:应用功能磁共振成像(fMRI)技术观察按揉6例正常人左侧委中穴前后脑内愉悦回路核团的信号变化。结果:按揉委中穴可引起脑内愉悦回路双侧杏仁核、双侧下丘脑和右侧伏隔核的信号明显升高(P〈0.05-0.01)。结论:按揉委中穴可兴奋脑内愉悦回路的核团,从而产生愉悦效应,这可能是推拿作用的中枢机制之一。

关 键 词:推拿  委中穴  脑愉悦回路  功能磁共振成像

Effects of Kneading Weizhong(B40)Acupoint on Brain Reward Circuitry
LI Zheng-yu,SUN Xi-wen,ZHANG Xiao-chu,CHEN Pei-qing,SHEN Xue-yong,YAN Jun-tao.Effects of Kneading Weizhong(B40)Acupoint on Brain Reward Circuitry[J].Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai,2008,22(4):51-53.
Authors:LI Zheng-yu  SUN Xi-wen  ZHANG Xiao-chu  CHEN Pei-qing  SHEN Xue-yong  YAN Jun-tao
Institution:LI Zheng-yu SUN Xi-wen ZHANG Xiao-chu CHEN Pei-qing XHEN Xue-yong YAN Jun-tao(1. Acupuncture & Tuina College,Shanghai University of Traditional Chinese Medicine;2. Shanghai Huadong Hospital;3. University of science and Technology of China;4. Yueyang Hospital of Integrative Chinese & Western Medicine Affiliated to Shanghai University of TCM)
Abstract:Objective: To study the effects of kneading Weizhong (BL 40) acupoint on brain reward circuitry. Methods: The functional magnetic resonance imaging (fMRI) technique was adopted to observe the signal changes of the nuclei of the brain reward circuitry in six healthy people receiving kneading manipulation at Weizhong (BL 40) acupoint. Results: Signals of the nuclei of the brain reward circuitry increase after kneading in bilateral amygdaloid nucleus and hypothalamus, and right nucleus accumbens septi(P〈0.05-0.01). Conclusion: Kneading Weizhong(BL 40) acupoint can excite the nuclei of the brain reward circuitry and hence produce pleasure effects, which may be one of the central mechanisms of Tuina therapy.
Keywords:Tuina  Weizhong(BL 40)  brain reward circuity  functional magnetic resonance imaging(fMRI)
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