X线对小鼠毛髓细胞数影响及β-胡萝卜素的防护作用 |
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摘 要: | 作者观察了受到不同剂量X射线照射后BALB/c鼠毛髓细胞计数(themedullarycellcounts,MCC)的变化,并研究了β-胡萝卜素(β-carotene,BC)对毛髓细胞的辐射防护作用。结果表明:1~5Gy照射后MCC随剂量增加而降低,每Gy平均减少15.87%。2.5Gy照前3天以50mg/kgBC每天1次灌胃能有效地保护毛囊增殖能力,维持MCC近正常值。
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关 键 词: | β-胡萝卜素,毛髓细胞计数,X射线 |
Influence of X-ray irradiation on hair medullary cell counts and radioprotective effect of β
-carotene |
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Authors: | Wang Xiaomei Ye Fei Su Shijie |
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Institution: | Department of Radiatiom Protection |
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Abstract: | The author observed the changes in the hair medullary cell counts( MCC)inBALB/c
mice after various doses of X-rays irradiation, and the radioprotective actioin of β-carotene(BC
) on MCC was also investigated.The results showed that MCC reduced with theincrease in
dosage after 1-5 Gy X-irradiation. The mean reduction of MCC was 15. 87%per Gy.The mice
were fed on with 50mg/kg BC once daily for three days before 2.5 Gy X-irradiation,the
proliferative activity of the hair follicles was protected efficiently and the normal MCC
wasmaintained. |
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Keywords: | β-carotene medullary cell counts(MCC) X-rays irradiation |
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