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X线对小鼠毛髓细胞数影响及β-胡萝卜素的防护作用
摘    要:作者观察了受到不同剂量X射线照射后BALB/c鼠毛髓细胞计数(themedullarycellcounts,MCC)的变化,并研究了β-胡萝卜素(β-carotene,BC)对毛髓细胞的辐射防护作用。结果表明:1~5Gy照射后MCC随剂量增加而降低,每Gy平均减少15.87%。2.5Gy照前3天以50mg/kgBC每天1次灌胃能有效地保护毛囊增殖能力,维持MCC近正常值。

关 键 词:β-胡萝卜素,毛髓细胞计数,X射线

Influence of X-ray irradiation on hair medullary cell counts and radioprotective effect of β -carotene
Authors:Wang Xiaomei  Ye Fei  Su Shijie  
Institution:Department of Radiatiom Protection
Abstract:The author observed the changes in the hair medullary cell counts( MCC)inBALB/c mice after various doses of X-rays irradiation, and the radioprotective actioin of β-carotene(BC ) on MCC was also investigated.The results showed that MCC reduced with theincrease in dosage after 1-5 Gy X-irradiation. The mean reduction of MCC was 15. 87%per Gy.The mice were fed on with 50mg/kg BC once daily for three days before 2.5 Gy X-irradiation,the proliferative activity of the hair follicles was protected efficiently and the normal MCC wasmaintained.
Keywords:β-carotene  medullary cell counts(MCC)  X-rays irradiation
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