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针药结合疗法对免疫性不育大鼠血清抗精子抗体的影响
引用本文:何燕萍,唐纯志,梁国珍,李功营,林锦泉,李万瑶,赖秀丽.针药结合疗法对免疫性不育大鼠血清抗精子抗体的影响[J].广州中医药大学学报,2001,18(2):140-143.
作者姓名:何燕萍  唐纯志  梁国珍  李功营  林锦泉  李万瑶  赖秀丽
作者单位:1. 广州中医药大学第一附属医院妇科,
2. 广州中医药大学针灸推拿学院,
基金项目:卫生部立项课题!(编号 :98- 1- 10 7)
摘    要:【目的】观察针药结合疗法对免疫性不育大鼠模型血清抗精子抗体的影响。【方法】将 80只SD大鼠分为 4组 ,采用主动免疫法建立血清抗精子抗体 (ASAb)阳性大鼠模型 ,并于造模时同期分别用针刺 (取穴关元俞、次 )、归肾液 (由熟地、菟丝子、女贞子、淮山、枸杞子、桑寄生、山萸肉等组成 )及针药结合治疗。【结果】针刺结合归肾液治疗组SD大鼠血清ASAb阴性率明显高于归肾液、针刺治疗组 (P <0 .0 5及P <0 .0 1)。【结论】说明针药结合有抑制ASAb产生的作用。

关 键 词:免疫性不育  针灸疗法  中医药疗法  抗精子抗体  归肾液
文章编号:1007-3213(2001)02-0140-04
修稿时间:2001年1月9日

Effect of Acupuncture Combined with Guishen Decoction on Serum ASAb Level of Rat Models with Immulogical Infertility
HE Yanping ,TANG Chunzhi ,LIANG Guozhen ,LI Gongying ,LIN Jinquan ,LI Wanyao ,LAI Xiuli.Effect of Acupuncture Combined with Guishen Decoction on Serum ASAb Level of Rat Models with Immulogical Infertility[J].Journal of Guangzhou University of Traditional Chinese Medicine,2001,18(2):140-143.
Authors:HE Yanping  TANG Chunzhi  LIANG Guozhen  LI Gongying  LIN Jinquan  LI Wanyao  LAI Xiuli
Institution:HE Yanping 1,TANG Chunzhi 2,LIANG Guozhen 1,LI Gongying 1,LIN Jinquan 2,LI Wanyao 2,LAI Xiuli 2
Abstract:Objective To explore the effect of acupuncture combined with Guishen Decoction (GD) on serum antisperm antibody (ASAb) level of rat models with immunological infertility. Methods Active immunization was used to establish rat models with positive serum ASAb. Eighty SD rats were alloc ated to four group s: Group A (treated with acupuncture and GD), Group B( treated with GD), Group C (treated with acupuncture), Group D (model control group). GD is composed of Ra dix Re hmanniae Praeparata, Semen Cuscutae, Fructus Ligustri Lucidi, Rhizoma Dioscorae, Fructus Lycii, Ramulus Loranthi, etc.. Results The negative rate of serum A SAb in Group A was significant higher than that in Group B and Group C (P< 0.05 ,P< 0.01 respectively). Conclusion Acupunctur e combined with GD exerts a certain effect in inhibiting the formation of serum ASAb.
Keywords:INFERTILITY/ TCD therapy  INFERTILITY/ acu_mox therap y  GUISHEN DECOCTION/ther  use  ANTISPERM ANTIBODY  KIDNEY-REINFORCING DRUGS/ther  use  POINT BL26  POINT BL32  DISEASE MODELS  ANIMAL  RATS
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