代谢综合征患者中医体质分析

【目的】分析代谢综合征(MS)患者的中医体质特征,研究不同体质的MS患者的临床特征,以期为MS的治疗和调养提供个体化的思路。【方法】收集328例MS患者的身高、体质量、体质量指数(BMI)、腰围、血压、血糖、血脂包括甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)]等指标,并根据《中医体质分类与判定自测表》对所纳入的MS患者进行标准化的中医体质类型分类。【结果】(1)本研究所纳入的328例MS患者中,TG水平升高或已接受相应治疗,合并血压升高或已接受相应治疗,或此前已诊断为高血压的患者最多,共41例,占12.50%。(2)中医体质分析以偏颇体质占绝大多数,共308例,占93.90%。偏颇体质中痰湿质最多见,共78例,占23.78%,其他依次为湿热质、气郁质、兼夹体质、气虚质、阳虚质、血瘀质、阴虚质、特禀质;平和质共20例,占6.10%。(3)痰湿质MS患者的体质量及BMI与平和质MS患者比较,差异有统计学意义(P0.05);痰湿质MS患者的TG与特禀质MS患者比较,差异有统计学意义(P0.05)。【结论】本研究所纳入的MS患者均具有典型的MS临床表现,中医体质辨识的结果提示MS以痰湿质、湿热质和气郁质为多见,对MS的治疗和护理调养应建立在对体质辨识的基础上,针对不同的体质特征采取相应的治疗和护理调养措施,实现个体化诊疗,充分体现了以人为本,因人制宜的思想。

Analysis of Traditional Chinese Medicine Constitution of Patients with Metabolic Syndrome

Objective To investigate the characteristics of traditional Chinese medicine(TCM) constitution of patients with metabolic syndrome(MS), so as to provide individualized therapy for the treatment and rehabilitation of MS. Methods The data of a total of 328 MS patients were collected, covering body height, body mass,body mass index(BMI),waist circumference,blood pressure,blood glucose,blood lipids such as triglyceride(TG),total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C), etc.. TCM constitution types of the MS patients were classified according to Self-rating Scale for Traditional Chinese Medicine Constitution Classification and Discrimination. Results (1)In the 328 cases,the patients with increased TG or having treated with lipid-lowering therapy,the patients complicated with increased blood pressure or having treated with antihypertensive therapy,and the patients with the previous diagnosis of hypertension were dominant,accounted for 41 cases(12.50%).(2)Bias constitution was predominant, showing in 308 cases and accounting for 93.90%. Phlegm-damp constitution was mostly commonly seen in the bias constitution, accounted for 78 cases(23.78%). And then the damp-heat constitution, Qi stagnation constitution, complicated constitution, Qi deficiency constitution, yang deficiency constitution, blood-stasis constitution, yin deficiency constitution and specific constitution came next orderly. Twenty patients had the harmony constitution, accounting for 6.10%. (3)MS patients with phlegm-damp constitution had higher body mass and BMI than the patients with harmony constitution, the difference being significant (P < 0.05). The differences of TG were significant between the phlegm-damp constitution and the specific constitution(P <0.05). Conclusion The included MS patients have typical clinical manifestations, and their TCM constitution types are commonly seen as phlegm-damp constitution,damp-heat constitution,and Qi stagnation constitution. The results of constitution discrimination will supply evidence for the individualized therapy for the treatment and rehabilitation of MS patients.