广州地区献血者梅毒感染情况分析

目的：对广州地区献血者进行血清学梅毒筛查与分析，了解献血者梅毒感染状况，为安全输血制订梅毒预防措施提供参考数据。方法：梅毒血清学初筛试验采用TRUST试验，阳性样本均采用TPPA试验进行确认。结果：7年（1995－2001年）献血人数为546098，梅毒阳性感染2060人，总阳性率为0．38％，男性阳性率（1124例，55％）高于女性（936例，45％）；7年梅毒阳性率呈逐年上升趋势，且95％的梅毒感染者年龄在20－39岁；近3年（1999－2001）郊区农村无偿献血者梅毒阳性率较高（分别为0．80％、0．98％、1．18％），流动人口无偿献血者梅毒阳性率也偏高（分别为0．49％、0．43％、0．68％）。结论：广州地区献血者梅毒阳性率呈逐年上升趋势，且感染者以青壮年为主，年龄在20－39岁；近3年来郊区农民和流动人口无偿献血梅毒阳性率上升较快，提示卫生防预部门应加强对郊区农民尤其是性活跃期年轻人的性病预防宣传教育工作，并联合采供血部门尽快出台安全采血措施与规范，以保证临床用血的安全性。

Analysis of Syphilis Infection Among Blood Donors in Guangzhou

Objective] To investigate the distribution of blood donors with syphilis in Guangzhou and to provide scientific evidence for the establishment of preventive strategies. Methods] The blood donors in Guangzhou from 1995 to 2001 were tested by TRUST, and then were confirmed by TPPA. Results] Among 546 098 donors, 2 060 were found syphilis positive (the positive rate being 0.38%) , in which 1 124 (55%) were male and 936 (45%) were female. The positive rate of syphilis increased during 1995 - 2001 and 95% of the positive was in the age group of 20 - 39. In the past three years (from 1999 to 2001) , positive rate of syphilis in suburban voluntary donors was high (0.80% , 0.98% , 1.18% in 1999, 2000 and 2001 respectively). So was that in the voluntary donors in floating population ( 0.49%, 0.43%, 0.68% respectively) . Conclusion] The positive rate of syphilis among the blood donors in Guangzhou increased annually from 1995 to 2001 and the majority of the infected were the young, ranging from 20 to 39 years old; and the positive rate of syphilis in the donors of suburban and floating population increased at a rapid rate. It is suggested that the sanitation and antiepidemic organization should take effective measures to strengthen sexually transmitted disease prevention and education among rural population, especially in the youth to ensure safe blood transfusion.