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理脾化痰降脂片治疗高脂血症的临床研究
引用本文:李任先,刘国普,曾益宏,熊文生. 理脾化痰降脂片治疗高脂血症的临床研究[J]. 广州中医药大学学报, 1999, 16(2): 98-102
作者姓名:李任先  刘国普  曾益宏  熊文生
作者单位:1. 广州中医药大学,广州,510405
2. 广州中医药大学第一附属医院,广州,510405
基金项目:国家中医药管理局科研基金!922181
摘    要:为检验自行研制的中药复方制剂理脾化痰降脂片的临床疗效,将符合条件的80例高脂血症患者分层随机分为理脾化痰降脂片治疗组50例,力平脂对照组30例,以单盲法进行临床观察和检测患者治疗前后血脂五项,血液流变学,自由基三项等相关指标。结果;理脾化痰降脂片的调脂疗效及调脂的稳定性好于力平脂;对血液流变学,自由基三项及主要临床症状等指标的改善优于力平脂;

关 键 词:高脂血症/中药疗法  血液流变学/药物作用  过氧化脂质类/血液  谷胱甘肽过氧化酶类/血液  超氧化物岐化酶/血液  @理脾化痰降脂片/治疗应用  理气药/治疗应用  化痰药(中药)/治疗应用

A Clinical Study of Lipi Huatan Jiangzhi Tablet for Hyperlipemia
LI Ren-xian,LIU Guo-pu,ZENG Yi-hong,XIONG Wen-sheng. A Clinical Study of Lipi Huatan Jiangzhi Tablet for Hyperlipemia[J]. Journal of Guangzhou University of Traditional Chinese Medicine, 1999, 16(2): 98-102
Authors:LI Ren-xian  LIU Guo-pu  ZENG Yi-hong  XIONG Wen-sheng
Abstract:To investigate the therapeutic effects of Lipi Huatan Jiangzhi Tablet(LHJT),80 cases of hyperlipenda were landomly allocated to LHJT group(50) and lypanthy group(30) and single-blindedtrial was applied.Blood lipids(total cholesterol,triglyceride,high density lipoprotein,apoprotein A andapoprotein B),blood theology and free radicals(lipid peroxide, superotide dismutase and glutathionesuperokidase) were observed.The results showed that the regulatory effect on lipid medslism in LHJTgroup was better and more stable; blood theology, free radicals and the main symptoms were more improved as comapared with lypanthy group. Meanwhile,the total effective rate of LHJT for patients withspleen-deficiency and phlegm-stagnation syndrome was higher than that with other TCM syndromes(P<0.05).It is analed that LHJT exerts a certain effect for hperlipemia.
Keywords:HYPERLIPIDEMIA/TCD ther  BLOOD RHEOLOGY/drug eff.  LIPID PEROXIDES/blood  GLUTATHIONE PEROXIDASE/blood  SUPEROXIDE DISMUTASE/blood  @LIPI HUATAN JIANGZHITABLET/ther. use  QI- REGULATING DRUGS /ther. use  EXPECTORANTS (TCD) /ther.use
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