加味逍遥散联合腹针引气归元治疗帕金森病吞咽障碍

【目的】观察加味逍遥散联合腹针引气归元治疗帕金森病(PD)吞咽障碍的疗效,探讨治疗PD吞咽障碍的更佳方法。【方法】选取42例PD合并吞咽功能障碍患者,随机分为对照组和治疗组各21例。2组均接受吞咽功能训练。在此基础上,治疗组予以服用加味逍遥散联合腹针引气归元治疗,对照组予以常规西药治疗(多潘立酮和多巴丝肼)。比较2组治疗3周后吞咽困难评分变化情况及治疗有效率。【结果】(1)治疗组全部病例完成试验,对照组有2例病例中途自动退出试验,最终共40例病例完成试验。(2)治疗3周后,2组的吞咽困难评分均较治疗前有明显改善(P0.01),且治疗组的改善作用明显优于对照组,差异有统计学意义(P0.05)。(3)治疗3周后,治疗组的总有效率为95.24%,明显优于对照组的52.63%,2组比较,差异有统计学意义(P0.01)。(4)本研究除3例患者出现胃肠道反应(治疗组1例、对照组2例)外,未观察到其他不良反应。【结论】加味逍遥散联合腹针引气归元治疗能较好地改善PD患者的吞咽功能障碍。

Clinical Observation of Modified Xiaoyao Powder Plus Abdominal Needling for Conducting Fire Back to Its Source in Treating Swallowing Dysfunction in Parkinson's Disease

Objective To investigate the therapeutic effects of modified Xiaoyao Powder combined with abdominal needling for conducting fire back to its source for the treatment of swallowing dysfunction in Parkinson's disease, and to explore a more effective therapy for swallowing dysfunction in Parkinson's disease. Methods Forty-two Parkinson's disease patients suffering from swallowing dysfunction were divided into treatment group and control group, 21 cases in each group. The patients in both groups received routine swallowing function training. In addition to the training, the treatment group was treated with modified Xiaoyao Powder combined with abdominal needling for conducting fire back to its source, and the control group was given conventional western medicine of Domperidone and Levodopa Benserazide Hydrochloride. After treatment for 3 weeks, we compared the dysphagia scores and effective rate of the two groups. Results (1) All of the patients in the treatment group completed the trial, but 2 cases of the control group dropped out. Therefore, a total of 40 cases completed the trial. (2) The dysphagia scores of the two groups were much improved after treatment (P<0.01 compared with those before treatment) , and the improvement of the treatment group was superior to that of the control group (P < 0.05). (3) After treatment for 3 weeks, the total effective rate of the treatment group was 95.24% and that of the control group was 52 . 63%, and the difference was statistically significant between the two groups(P<0.01).(4) Gastrointestinal reaction occurred in 3 cases(one from the treatment group and 2 from the control group) , but there were no other side effects found in both groups. Conclusion Modified Xiaoyao Powder combined with abdominal needling for conducting fire back to its source is more effective for the treatment of swallowing dysfunction in Parkinson's disease than routine western medicine treatment.