复方消风散联合背部走罐疗法治疗风热型慢性荨麻疹的疗效观察

【目的】观察复方消风散联合背部走罐疗法治疗风热型慢性荨麻疹的临床疗效。【方法】将56例风热型慢性荨麻疹患者随机分为试验组和对照组,每组各28例。对照组给予氯雷他定治疗,试验组在对照组的基础上给予口服自拟复方消风散联合背部走罐疗法治疗,连续治疗4周并随访8周。观察2组患者治疗前后症状积分和皮肤病生活质量指数(DLQI)评分的变化情况,评价2组患者的临床疗效及安全性,比较2组患者的复发情况。【结果】(1)治疗4周后,试验组的愈显率和总有效率分别为67.86%(19/28)、85.71%(24/28),对照组分别为46.43%(13/28)、82.14%(23/28),组间比较,试验组的愈显率和总体疗效均优于对照组,差异均有统计学意义(P<0.05)。(2)治疗后,2组患者的各项症状积分及总积分均较治疗前明显降低(P<0.05),且试验组的瘙痒程度、风团大小、风团持续时间等症状积分及总积分的降低程度均明显高于对照组,差异均有统计学意义(P<0.05)。(3)治疗后,2组患者的DLQI评分均较治疗前明显降低(P<0.05),且试验组DLQI评分的降低程度明显高于对照组,差异有统计学意义(P<0.05)。(4)疗程结束后8周,试验组的复发率为15.79%(3/19),低于对照组的23.08%(3/13),差异有统计学意义(P<0.05)。(5)治疗过程中,2组患者均无明显的不良事件发生。【结论】在西药治疗基础上配合复方消风散联合背部走罐疗法治疗风热型慢性荨麻疹疗效确切,其近期疗效和远期疗效均优于单独西药治疗。

Observation on the Curative Effect of Compound Xiaofeng Powder Combined with Back Moving Cupping Therapy on Chronic Urticaria of Wind-heat Type

Objective To observe the clinical efficacy of compound Xiaofeng Powder combined with back moving cupping therapy in the treatment of chronic urticaria(CU)of wind-heat type. Methods Fifty-six patients with wind-heat chronic urticaria were randomly divided into the trial group and the control group,with 28 patients in each group. The control group was treated with Loratadine tablets, while the trial group was treated with oral administration of self-prescribed compound Xiaofeng Powder combined with back moring cupping therapy for4 consecutive weeks and then was followed up for 8 weeks. The changes of symptom scores and dermatology life quality index(DLQI)scores in the two groups were observed before and after treatment. After treatment, the clinical efficacy and safety of the two groups were evaluated,and the recurrence in the two groups was compared.Results(1)After 4 weeks of treatment,the cured and markedly effective rate and the total effective rate in the trial group were 67.86%(19/28)and 85.71%(24/28),respectively,while those in the control group were 46.43%(13/28)and 82.14%(23/28), respectively. The intergroup comparison showed that the cured and markedly effective rate and the total effective rate of the trial group were superior to that of the control group, and the differences being statistically significant(P<0.05).(2)After treatment, the scores of each symptom and the overall symptom scores of the two groups were significantly decreased compared with those before treatment(P<0.05),and the effect on reducing the scores of the degree of pruritus,wheal size,duration of wheal and the overall symptom scores in the trial group was significantly superior to that in the control group,the differences being statistically significant(P<0.05).(3)After treatment,the DLQI scores in both groups were significantly decreased compared with those before treatment(P<0.05),and the effect on lowering the DLQI scores in the trial group was significantly superior to that in the control group,the difference being statistically significant(P<0.05).(4)Eight weeks after the completion of treatment,the recurrence rate of the trial group was 15.79%(3/19),lower than that of the control group23.08%(3/13)],and the difference being statistically significant(P<0.05).(5)During the treatment,there were no significant adverse events occurring in the two groups. Conclusion On the basis of western medicine treatment,the compound Xiaofeng Powder combined with back moving cupping therapy exerts certain effect in the treatment of wind-heat chronic urticaria,and its short-term efficacy and long-term efficacy are superior to those of the western medicine treatment alone.