阻塞性睡眠呼吸暂停/低通气综合征与高血压病相关性研究

目的：探讨研究阻塞性睡眠呼吸暂停/低通气综合征（OSAHS）和高血压病之间的关系及对血压昼夜变化节律的影响。方法：选取本科经多导睡眠呼吸监测（PSG）确诊为阻塞性睡眠呼吸暂停/低通气综合征（OSAHS）的患者160例,测量其血压,并对其危险度进行分级,分析患者呼吸暂停低通气指数（AHI）与高血压程度及危险度的关系。结果：以AHI分为三组,各组间高血压患病率比较差异有统计学意义（P〈0.01）。AHI严重程度与血压的程度及危险度呈正相关（P〈0.01）。结论：OSAHS作为高血压发病的危险因素,阻塞性睡眠呼吸暂停/低通气综合征（OSAHS）的高血压发生率明显高于健康人群;与单纯高血压患者相比,OSAHS患者血压昼夜变化节律存在明显差异。

Association between the Hypertension and Obstructive Sleep Apnea/Hypopnea Syndrome

Objective： To investigate the relationship between obstructive sleep apnea/hypopnea syndrome （ OSAHS ） and hypertension and its effect on blood pressure rhythm of day and night change.Method： Measured the Department after several sleep apnea monitoring （ PSG ） confirmed 160 cases of obstructive sleep apnea/hypopnea syndrome （ OSAHS ） in patients with blood pressure, and grading the risk, analysis of patients with apnea hypopnea index （ AHI ） relationship with the extent and risk of hypertension.Result： With AHI were divided into three groups, hypertension prevalence rate oi each group had statistically significant differences （ P〈0.01 ） .Correlation and risk the severity of AI-I and blood pressure were positive （ P〈0.01 ） . Conclusion： OSAHS as a risk factor for hypertension, obstructive sleep apnea/hypopnea syndrome （ OSAHS ） has significantly higher incidence of hypertension in healthy people; and simple compared to patients with hypertension, pronounced differences of circadian changes of blood pressure rhythm in patients with OSAHS.