两种化疗方案治疗胃癌的临床对比研究

目的：探讨FOLFIRI方案（CPT-11＋CF/5-Fu）及XELOX方案（奥沙利铂联合卡培他滨）在胃癌化疗中的临床疗效及不良反应。方法：将80例中晚期胃癌患者随机分为A组38例、B组42例,A组采用FOLFIRI方案治疗,B组采用XELOX方案治疗,进行疗效及成本对比分析。结果：A组与B组治疗效果比较差异无统计学意义（P〉0.05）,A组不良反应发生率高于B组,成本低于B组,差异有统计学意义（P〈0.05）。结论：两种化疗方案疗效相似,患者应根据自身情况选择合适的治疗方案。

The Comparative Clinical Study of Two Chemotherapy Regimens for Gastric Cancer

Objective： To research the the clinical efficacy and adverse reactions of FOLFIRI regimen （ CPT-I I＋CF/5-Fu ） and XELOX regimen （ oxaliplatin combined with capecitabine ） in gastric cancer chemotherapy.Method： 80 cases of advanced gastric cancer patients were randomly divided into two groups. Group A 38 cases, group B 42 cases, group A regimen of irinotecan （ CPT-11 ） ＋fluorouracil （ 5-FU ） / calcium folinate （ CF ） , group B, oxaliplatin ＋ eapecitabine Bin regimen, analize the efficacy and cost. Result： Group A and group B was not significant difference in the treatment （ P〉0.05 ）, the adverse incidence of group A was higher than that in group B, the cost was lower than group B, there were significant differences （ P〈0.05 ）. Conclusion： The efficacy of two chemotherapy regimens, patients should be selected according to their appropriate treatment program.