人羊膜在牙种植术中的临床应用研究

目的：观察人羊膜联合生物骨粉（Bio-Oss）引导骨再生术应用于牙种植的临床疗效。方法：将32例骨量不足的患者按随机数字表法分为A、B两组各16例。两组植入种植体同时植入Bio-Oss与自体骨的混合物，A组表面覆盖人羊膜，B组表面覆盖金属钛膜。术后1、3、6、12个月通过临床检查及X线检查评价临床疗效。结果：两组植骨区新骨形成均良好，牙槽嵴外形丰满，种植体无松动脱落，均完成了冠修复。长期随访示A组骨吸收量更小，与B组比较差异有统计学意义（P〈0.01）。结论：人羊膜及金属钛膜联合引导骨再生术应用于种植区骨量不足的患者均可取得较好的疗效，但人羊膜组效果更佳。

Clinical Application of the Human Amniotic Membrane in Dental Implantation

Objective：To observe the clinical curative effect of amniotic membrane combined with Bio-Oss guided bone regeneration in dental implant.Method：32 cases of bone defects were randomly divided into the group A, B for 16 cases. While in the implantation of Bio-Oss and autogenous bone,the group A covered with human amniotic membrane,the group B with titanium membrane. The clinical efficacy after 1,3,6 and 12 months’ treatment were evaluated by clinical examination and X-ray examination.Result：The two groups had a good bone formation in bone graft area,alveolar ridge shape plump,no implant got loosen or missed,and finally the crown were all completed. The long term follow-up showed there was less bone absorption in the group A,and compared with the group B,the difference was statistically significant（P〈0.01）.Conclusion：Human amniotic membrane and titanium membrane combined with guided bone regeneration technique applied in the planting area of bone deficiency patients can affect well,and human amniotic membrane get a more significant effect than titanium membrane.