| 基于网络药理学策略探讨四君子汤治疗癌性恶病质的潜在机制 |
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| 引用本文： | 陈江锋,林芝娴,郭勇.基于网络药理学策略探讨四君子汤治疗癌性恶病质的潜在机制[J].浙江中西医结合杂志,2022,32(2):122-128. |
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| 作者姓名： | 陈江锋 林芝娴 郭勇 |
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| 作者单位： | 杭州市肿瘤医院,杭州市第三人民医院,浙江省中医院 |
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| 摘 要： | 目的 基于网络药理学方法探讨四君子汤治疗癌性恶病质的可能机制.方法 本研究采用一个全面的网络药理学策略,由四个顺序模块组成:靶点预测、网络构建、分子对接、GO和KEGG富集分析.结果 四君子汤中的7,9(11)-dehydropachymic acid和Taraxerol化合物可能通过作用于INS,PCK2,FABP3...
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| 关 键 词： | 四君子汤 癌性恶病质 网络药理学 分子对接 潜在机制 |
| 收稿时间： | 2021/8/10 0:00:00 |
| 修稿时间： | 2021/12/24 0:00:00 |
Network pharmacology-based strategy to investigate the underlying mechanisms of Sijunzi Decoction in the treatment of cancer cachexiaCHEN Jiang-feng 1*, LIN Zhi-xian 2, GUO Yong 3 |
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| Chen Jiang-feng,and.Network pharmacology-based strategy to investigate the underlying mechanisms of Sijunzi Decoction in the treatment of cancer cachexiaCHEN Jiang-feng 1*, LIN Zhi-xian 2, GUO Yong 3[J].Zhejiang Journal of Integrated Traditional Chinese and Western Medicine,2022,32(2):122-128. |
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| Authors: | Chen Jiang-feng and |
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| Institution: | (Department of Integrated Traditional Chinese and Western Medicine Oncology Ward number 1,Hangzhou Cancer Hospital,Hangzhou 310002,China;Department of Oncology,The Third People's Hospital of Hangzhou,Hangzhou,310009,China;Department of oncology,Zhejiang Provincial Hospital of Traditional Chinese Medicine,Hangzhou 310006,China) |
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| Abstract: | |
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| Keywords: | Sijunzi decoction Cancer Cachexia Network Pharmacology Molecular Docking Underlying Mechanisms |
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