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带蒂心包重建右室流出道的动物实验研究
引用本文:方刚,万荣华.带蒂心包重建右室流出道的动物实验研究[J].宁夏医科大学学报,2003,25(4):247-248,252.
作者姓名:方刚  万荣华
作者单位:宁夏医学院附属医院胸心外科,宁夏医学院附属医院胸心外科 银川 750004,银川 750004
摘    要:目的:观察带蒂心包重建右室流出道的效果。方法:在20条杂种狗的主肺动脉上用带蒂自体心包补片,同时在右心耳上用离体自体心包补片。术后l、2年分批取出移植心包及正常心包,分别进行病理检查。结果:带蒂心包组织柔软,弹性良好,无钙化;大量毛细血管增生,成纤维细胞正常且核膜存在。不带蒂心包苍白,组织僵硬,弹性差,灶性区域纤维素样坏死,钙化灶形成;成纤维细胞和毛细血管稀少,核碎裂。术后l、2年结果相比较,上述差别明显。结论:带蒂心包有良好的组织生物学活性,是重建右室流出道的一种有效方法。

关 键 词:右室流出道重建  带蒂心包    实验研究  组织生物学
文章编号:1005-8486(2003)04-0247-02

A Experimental Study on Right Ventricular Outflow Tract Reconstruction With Pedunculated Pericardium
FANG Gang,WAN Rong-hua.A Experimental Study on Right Ventricular Outflow Tract Reconstruction With Pedunculated Pericardium[J].Journal of Ningxia Medical College,2003,25(4):247-248,252.
Authors:FANG Gang  WAN Rong-hua
Abstract:Objective: To evaluate the practical feasibility of right ventricular outflow tract reconstruction by using pedunculated pericardium. Methods: Dog models with pedunculated pericardium patch autografted to main pulmonary artery for mending a hole on it and with isolated pericardium patch autografted to right auricle of heart for mending a hole on it were surgically established. One year and two years after operation, the autografted pericardium was histopathologically examined. Results: The pedunculated pericardium looked soft and elasticity-abundant , presented normal fibroblast and proliferating capillaries, and showed no calcification. On the contrary, the isolated pericardium looked pale and stiff; calcification was obvious, capillaries and fibroblasts were seen scarcely, karyo-rrhexis and fibrinoid necrosis were apparent. Conclusion: The pedunculated pericardium possesses vigorous biological activity and is an effective material to reconstruct right ventricular outflow tract.
Keywords:pedunculated pericardium  right ventricular outflow tract  reconstruction
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