大肠多发原发性癌:危险因素、诊治和预防(附8例报告)

综述分析1954～84年国内外文献,探讨了大肠多发原发性癌的诊断标准、发病情况、临床表现、发病危险因素、外科处理以及预防和诊断检测技术等问题,强调了大肠腺瘤,遗传基础、免疫缺陷、慢性溃疡性结肠炎等在发病上的作用,及高危险组患者应按方案进行常规检测监护之重要性。述介了大肠多发原发性癌系一种原发性大肠癌多中心发生的形式,在诊治上前者与后者有一致性,亦各有其独特性。报告宁夏医学院附属医院肿瘤科1977～84年收治的8例住院大肠多发原发性癌病例的临床资料,对诊治经过进行了初步总结。

Multiple Primary Carcinomas of Large Intestine:Risk Factors, Diagnosis, Treatment,and Prophylaxis

Through review of pertinent articles from year 1954 tol984,certain aspects concerning the criteria for diagnosis as well as the prevalence, clinical manifestations, potential risk factors, surgical management, mand diagnostic techniques of multiple primary colorectal malignancies were analyzed and discussed.The prevalent role played by adenomas of large bowel,inheritance predisposition,immunodeficincy,and chronic ulceratve colitis as well as the importance of application of routine assaying and monitoring in accordance with surveillance programs for high-risk patients were emphasized.Data suggested that multiple primary colorectal malignancies are manifestations of multicentricity of origin of primary colorectal carcinomas,and that the diagnosis and treatment of both are fundamentally identical, yet still possessing individualities in each of the two. Eight cases of multiple primary colorectal carcinomas admitted to our Department of Oncology,Affiliated Hospital,Ningxia Medical College between years 1977 and 1984 were also reported as an attendant attachment,together with the atthor's preliminary experiences in diagnosing and treating these cases.