| 自拟肠僻方治疗溃疡性结肠炎60例疗效观察 |
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| 引用本文： | 张建林,高鹏,翟春涛.自拟肠僻方治疗溃疡性结肠炎60例疗效观察[J].世界中西医结合杂志,2009,4(12):888-889. |
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| 作者姓名： | 张建林 高鹏 翟春涛 |
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| 作者单位： | 1. 山西省平定县中医院,山西,平定,045200
2. 山西中医学院,山西,太原,030024 |
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| 摘 要： | 目的观察自拟肠僻方对溃疡性结肠炎患者肠黏膜κ基因结合核转录因子（NF-κB）及信号转导和转录激活因子6（STAT6）表达的影响及其疗效。方法120例病例随机分为两组,每组60例。对照组给予甲硝唑栓,治疗组给予自拟肠僻方治疗。4w为1个疗程,2个疗程后比较疗效及检测溃疡性结肠炎患者肠黏膜NF-κB及STAT6的表达。结果两组病例治疗后临床疗效及黏膜病变疗效比较有显著性差异,两组病例治疗后NF-κBp65及STAT6的表达均降低,两组比较有显著性差异。结论自拟肠僻方能抑制患者的NF-κBp65及STAT6的活化及表达,从而抑制相关炎性因子的表达,控制腹泻等临床症状,并促进患者受损黏膜组织的恢复。
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| 关 键 词： | 溃疡性结肠炎 自拟肠僻方 NF-κB STAT6 |
Observation of the Efficacy of Self-Prepared Chang Pi Fang in Treatment of 60 Cases of Ulcerative Colitis |
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| ZHANG Jian-lin,GAO Peng,ZHAI Chun-tao.Observation of the Efficacy of Self-Prepared Chang Pi Fang in Treatment of 60 Cases of Ulcerative Colitis[J].World Journal Of Integrated Traditional and Wesrern Medicine,2009,4(12):888-889. |
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| Authors: | ZHANG Jian-lin GAO Peng ZHAI Chun-tao |
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| Institution: | ZHANG Jian - lin , GAO Peng , ZHAI Chun - tao (1. Shanxi Pingding Hospital of Traditional Chinese Medicine ,Yangquan Shanxi 045200 ;2. Shanxi College of Traditional Chinese Medicine, Taiyuan Shanxi 030024) |
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| Abstract: | |
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| Keywords: | NF-KB STAT6 |
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