| 晚期非小细胞肺癌痰湿证与外周血免疫指标相关性研究 |
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| 引用本文： | 龚亚斌,王中奇,徐振晔.晚期非小细胞肺癌痰湿证与外周血免疫指标相关性研究[J].世界中西医结合杂志,2013,8(4):395-396,416. |
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| 作者姓名： | 龚亚斌 王中奇 徐振晔 |
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| 作者单位： | 龚亚斌 (上海中医药大学附属龙华医院,上海,200032)； 王中奇 (上海中医药大学附属龙华医院,上海,200032)； 徐振晔 (上海中医药大学附属龙华医院,上海,200032上海市中医药研究院,上海,200032)； |
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| 基金项目： | 上海市浦东新区科技发展基金创新基金（No.PKJ2008-Y32）1 |
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| 摘 要： | 目的探讨晚期非小细胞肺癌(NSCLC)痰湿证与细胞免疫功能相关性。方法共纳入晚期NSCLC痰湿证患者190例,收集外周血标本,检测外周血细胞免疫功能指标(CD3+、CD4+、CD8+、CD4+/CD25+、CD3-/CD56+16+、CD8+/CD28+、CD4+/CD45RA、CD4/CD8),应用二元Logistic回归分析方法分析痰湿证与外周血细胞免疫功能指标相关性。结果痰湿证与CD3-/CD56+16+水平有相关性(P=0.030),与CD3+、CD4+、CD8+、CD4+/CD25+、CD8+/CD28+、CD4+/CD45RA、CD4/CD8水平无相关性(P>0.05)。结论晚期NSCLC痰湿证与血清CD3-/CD56+16+细胞水平相关。
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| 关 键 词： | 晚期非小细胞肺癌 痰湿证 细胞免疫 二元Logistic回归 |
Correlative Research of Phlegm Damp Pattern/Syndrome of Advanced Non -Small Cell Lung Cancer and Peripheral Blood Immune Index |
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| GONG Ya-bin,WANG Zhong-qi,XU Zhen-ye.Correlative Research of Phlegm Damp Pattern/Syndrome of Advanced Non -Small Cell Lung Cancer and Peripheral Blood Immune Index[J].World Journal Of Integrated Traditional and Wesrern Medicine,2013,8(4):395-396,416. |
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| Authors: | GONG Ya-bin WANG Zhong-qi XU Zhen-ye |
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| Institution: | GONG Ya - bin ,WANG Zhong - qi ,XU Zhen - ye ( 1. Affiliated Longhua Medicine of Shanghai University of Traditional Chinese Medicine, Shanghai 200032 ; 2. Shanghai Academy of Traditional Chinese Medicine, Shanghai 200032) |
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| Abstract: | Objective To explore the correlation between phlegm damp pattern/syndrome of ad- vanced non - small cell lung cancer（NSCLC） and cell immune function. Methods One hundred and ninety cases of advanced NSCLC were included and the peripheral blood sample was collected. The indexes of pe- ripheral blood cell immune function （ CD3 ＋ , CD4 ＋ , CD8＋ , CIM ＋/CD25 ＋ , CD3 -/CD56 ＋ 16 ＋ , CD8 ＋ / CD28 ＋ ,CIM ＋/CD45RA and CIM/CD8）were detected. The binary Logistic regression method was used to analyze the correlativity of phlegm damp pattern/syndrome and the peripheral blood cell immune function in- dexes. Results Phlegm damp pattern/syndrome was correlated with the level of CD3-/CD56 ＋ 16 ＋ （P = 0. 030） and was uncorrelated with the levels of CD3 ＋ , CD4 ＋ , CD8 ＋ , CIM ＋/CD25 ＋ , CD8 ＋/CD28 ＋ , CIM ＋ / CD45RA and CIM/CD8 （ P 〉 0.05 ）. Conclusion Phlegm damp pattern/syndrome of NSCLC is correlated with the level of CD3 -/CD56 ＋ 16 ＋ |
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| Keywords: | Non -Small Cell Lung Cancer（NSCLC） Phlegm Damp Pattern/Syndrome Cell Immu-nity Binary Logistic Regression |
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