53例肝硬化难治性腹水两种疗法的临床比较

目的探讨自体腹水浓缩后回输腹腔在肝硬化难治性腹水治疗的临床应用价值。方法肝硬化难治性腹水患者53例，随机分组，27例采用自身腹水浓缩腹腔回输方法治疗为治疗组，26例采用传统的放腹水加输白蛋白方法治疗为对照组。对两组各项指标进行对照分析。结果治疗组在尿量增加程度、内生肌酐清除率的改善、血清白蛋白增加程度、腹水量减少程度、低钠血症患者血钠的增加各方面均明显优于对照组。住院期间平均每个住院日白蛋白用量治疗组明显低于对照组，腹穿次数治疗组少于对照组。结论自体腹水浓缩回输腹腔治疗肝硬化难治性腹水安全有效，在消除腹水，纠正稀释性低钠血症，有效提高血清白蛋白量，改善肾功等方面均较传统放腹水加输白蛋白的方法更明显的疗效。

Comparison of Two Therapeutics for 53 Cases of Refractory Ascites Due to Cirrhosis

Objective To observe the therapeutic effects of reinfusion of ascites concentrated on refractory ascites due to cirrhosis.Methods 53 patients were randomly divided into two groups.Group A(n=27) was treated by reinfusion of ascites filtrated and concentrated and Group B(n=26) by routine draining ascites and infusing albumin.Results The therapeutic effects in group A was better in increasing urine,improving the clearance rate of endogenous creatinine,increasing blood albumin,decreasing ascites and correcting low blood sodium than group B.Conclusions Reinfusion of ascites concentrated is a safe and effective therapy for refractory ascites due to cirrhosis.It is better on decreasing ascites,correcting low blood sodium,increasing blood albumin and improving kidney function compared with the traditional method.