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冠心病患者高密度脂蛋白胆固醇状况分析
引用本文:汤涌,黄进,陆治平,杨明智.冠心病患者高密度脂蛋白胆固醇状况分析[J].实用全科医学,2006,4(4):386-387.
作者姓名:汤涌  黄进  陆治平  杨明智
作者单位:江苏省南京市胸科医院心内科,江苏省南京市胸科医院心内科,江苏省南京市胸科医院心内科,江苏省南京市胸科医院心内科
摘    要:目的分析高密度脂蛋白胆固醇及其他血脂成份和冠心病的关系。方法选择接受冠状动脉造影的208例患者,按冠状动脉造影结果分为冠心病组和非冠心病对照组,并且又将冠心病组分为单支病变和多支病变两个亚组。测定血液中高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)、总胆固醇(TCHO)含量进行分析。结果冠心病组和对照组比较,两组TG、LDL-C均无显著性差异。两组TCHO、HDL-C比较有显著性差异(P<0.05)。冠心病组中两亚组比较,TG、TCHO、LDL-C均无显著性差异,HDL-C有显著性差异(P<0.01)。其中,多发病变亚组HDL-C减少了21.9%。结论高密度脂蛋白胆固醇是不依赖其他血脂成份的冠心病独立危险因素,并且和冠心病的严重程度成正相关。

关 键 词:冠心病  血脂  高密度脂蛋白胆固醇
文章编号:1672-1764(2006)04-0386-02
收稿时间:2006-02-13
修稿时间:2006年2月13日

Association between Coronary Heart Disease and High Density Lipoprotein Cholesterol
TANG Yong , HUANG Jin , LU Zhiping ,et al..Association between Coronary Heart Disease and High Density Lipoprotein Cholesterol[J].Applied Journal Of General Practice,2006,4(4):386-387.
Authors:TANG Yong  HUANG Jin  LU Zhiping  
Institution:Department of Cardiology, Nanjing Chest Hospital, Nanjing 210029, China
Abstract:Objective To analyzed the relationship between coronary heart disease (CAD)and high density lipoprotein cholesterol(HDL-C) and other lipid in the blood plasma. Methods Two hundred and eight patients underwent coronary arteriography were distributed in coronary heart disease group (again were divided into single-vessel and multi-vessel group) and none coronary heart disease group according to the results of arteriography. The HDL-C, LDL-C, triglyceride (TG) and total cholesterol (TCHO) of blood plasma in the two groups were detected and analyzed. Results There was significantly difference in TCHO and HDL-C, while not in TG and LDL-C, in the two groups. HDL-C reduced by 21.9% in the multi-vessel subgroup compared with the signal-vessel subgroup (P<0.01). There was not difference in TCHO, TG and LDL-C between the two subgroups. Conclusions HDL-C is an independent risk factor for CAD, and has positive correlation to severity of CAD.
Keywords:Coronary heart disease  Blood fat  High density lipoprotein cholesterol
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